Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 232-252 of 10,326 articles
From combination early detection to multicancer testing: shifting cancer care toward proactive prevention and interception.

Identifying the presence of tumors at a very early stage or deciphering the process underlying their...

Identification of inflammation-related biomarkers and therapeutic targets for neurogenic bladder fibrosis via multi-omics analysis.

Inflammatory responses play a crucial role in the progression of pediatric neurogenic bladder (NB)-a...

Predicting the impact of climate warming on soil quality using bacteria and machine learning.

In the context of global warming, a substantial portion of global soil is in a state of degradation,...

Early transcriptional responses reveal cell type-specific vulnerability and neuroprotective mechanisms in the neonatal ischemic hippocampus.

Neonatal hypoxic-ischemic (H-I) brain injury, a leading cause of neurodevelopmental disabilities, se...

Liposome-encapsulated AICAR hydrogel regulates macrophage metabolic reprogramming via SIK1 activation to alleviate osteoarthritis.

BACKGROUND: Osteoarthritis (OA), the most prevalent joint disorder, is characterized by a complex et...

Advancements in Tuberculosis Diagnostics: An Update.

Tuberculosis (TB) is one of the major life-threatening diseases caused by a single pathogen which ha...

Decoding disease-specific ageing mechanisms through pathway-level epigenetic clock: insights from multi-cohort validation.

BACKGROUND: Ageing is a multifactorial process closely associated with increased risk of chronic dis...

Unraveling the oxidative stress landscape in diabetic foot ulcers: insights from bulk RNA and single-cell RNA sequencing data.

BACKGROUND: Oxidative stress plays a crucial role in the development of diabetic foot ulcers (DFU). ...

Uncovering key markers and therapeutic targets for renal fibrosis in diabetic kidney disease through bulk and single-cell RNA sequencing.

BACKGROUND: Diabetic kidney disease (DKD) is the major cause of chronic kidney failure, with tubuloi...

Computational Strategies to Enhance Vitamin B Biosynthesis Potential of Microbes.

Vitamin B is a vital nutrient for the normal functioning of many metabolic processes. It has a chara...

Machine learning combined with multi-omics to identify immune-related LncRNA signature as biomarkers for predicting breast cancer prognosis.

This study developed an immune-related long non-coding RNAs (lncRNAs)-based prognostic signature by ...

Tracing the evolutionary pathway of SARS-CoV-2 through RNA sequencing analysis.

The COVID-19 pandemic, driven by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), h...

DOLPHIN advances single-cell transcriptomics beyond gene level by leveraging exon and junction reads.

The advent of single-cell sequencing has revolutionized the study of cellular dynamics, providing un...

5-Hydroxymethylcytosine signatures as diagnostic biomarkers for septic cardiomyopathy.

At present, there are currently no molecular biomarkers for the early diagnosis of sepsis cardiomyop...

Divide-and-conquer strategy with engineered ossification center organoids for rapid bone healing through developmental cell recruitment.

Current approaches for bone repair predominantly target localized delivery of growth factors that ar...

Multiomic integration reveals subtype-specific predictors of neoadjuvant treatment response in breast cancer.

Neoadjuvant therapy has been widely used in breast cancer, but treatment response varies among indiv...

Breeding perspectives on tackling trait genome-to-phenome (G2P) dimensionality using ensemble-based genomic prediction.

Trait Genome-to-Phenome (G2P) dimensionality and "breeding context" combine to influence the realise...

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