Biochimica et biophysica acta. Reviews on cancer
Nov 20, 2023
Gynecological cancers including breast, cervical, ovarian, uterine, and vaginal, pose the greatest threat to world health, with early identification being crucial to patient outcomes and survival rates. The application of machine learning (ML) and ar...
Biochimica et biophysica acta. Reviews on cancer
Oct 18, 2023
Recent multi-omics studies, including proteomics, transcriptomics, genomics, and metabolomics have revealed the critical role of post-translational modifications (PTMs) in the progression and pathogenesis of Glioblastoma multiforme (GBM). Further, PT...
Biochimica et biophysica acta. Reviews on cancer
Feb 21, 2023
Deep learning (DL) is one of the most powerful data-driven machine-learning techniques in artificial intelligence (AI). It can automatically learn from raw data without manual feature selection. DL models have led to remarkable advances in data extra...
Biochimica et biophysica acta. Reviews on cancer
Jul 7, 2021
The recent deluge of genome-wide technologies for the mapping of the epigenome and resulting data in cancer samples has provided the opportunity for gaining insights into and understanding the roles of epigenetic processes in cancer. However, the com...
Biochimica et biophysica acta. Reviews on cancer
May 31, 2021
Pharmaceutical agents in oncology currently have high attrition rates from early to late phase clinical trials. Recent advances in computational methods, notably causal artificial intelligence, and availability of rich clinico-genomic databases have ...
Biochimica et biophysica acta. Reviews on cancer
May 29, 2021
Recent technological advances continue to expand the universe of big data in biomedicine along the four axes of variety, veracity, volume, and velocity, fueling innovations in research and discovery while transforming care delivery. These advances al...
Biochimica et biophysica acta. Reviews on cancer
May 28, 2021
Current applications of artificial intelligence (AI), machine learning, and deep learning in cancer research and clinical care are highly diverse-from aiding radiologists in reading medical images to predicting oncoprotein folding and dynamics. The l...
Biochimica et biophysica acta. Reviews on cancer
May 26, 2021
Pediatric cancer is a rare disease with a distinct etiology and mutational landscape compared with adult cancer. Multi-omics profiling of retrospective and prospective cohorts coupled with innovative computational analysis have been instrumental in u...
Biochimica et biophysica acta. Reviews on cancer
Apr 29, 2021
Breast ductal carcinoma in situ (DCIS) is a preinvasive lesion that is considered to be a precursor to invasive breast cancer. Nevertheless, not all DCIS will progress to invasion. Current histopathological classification systems are unable to predic...