Journal of the American Medical Informatics Association : JAMIA
May 1, 2020
OBJECTIVE: Non-small cell lung cancer is a leading cause of cancer death worldwide, and histopathological evaluation plays the primary role in its diagnosis. However, the morphological patterns associated with the molecular subtypes have not been sys...
Journal of the American Medical Informatics Association : JAMIA
May 1, 2020
OBJECTIVE: Predicting patient outcomes using healthcare/genomics data is an increasingly popular/important area. However, some diseases are rare and require data from multiple institutions to construct generalizable models. To address institutional d...
Journal of the American Medical Informatics Association : JAMIA
May 1, 2020
OBJECTIVES: Sharing patient data across institutions to train generalizable deep learning models is challenging due to regulatory and technical hurdles. Distributed learning, where model weights are shared instead of patient data, presents an attract...
Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2020
OBJECTIVE: Implementation of machine learning (ML) may be limited by patients' right to "meaningful information about the logic involved" when ML influences healthcare decisions. Given the complexity of healthcare decisions, it is likely that ML outp...
Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2020
OBJECTIVE: To build a knowledge base of dietary supplement (DS) information, called the integrated DIetary Supplement Knowledge base (iDISK), which integrates and standardizes DS-related information from 4 existing resources.
Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2020
OBJECTIVE: Reliable longitudinal risk prediction for hospitalized patients is needed to provide quality care. Our goal is to develop a generalizable model capable of leveraging clinical notes to predict healthcare-associated diseases 24-96 hours in a...
Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2020
INTRODUCTION: Classifying whether concepts in an unstructured clinical text are negated is an important unsolved task. New domain adaptation and transfer learning methods can potentially address this issue.
Journal of the American Medical Informatics Association : JAMIA
Apr 1, 2020
OBJECTIVE: Depression is currently the second most significant contributor to non-fatal disease burdens globally. While it is treatable, depression remains undiagnosed in many cases. As mobile phones have now become an integral part of daily life, th...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2020
OBJECTIVES: Current machine learning models aiming to predict sepsis from electronic health records (EHR) do not account 20 for the heterogeneity of the condition despite its emerging importance in prognosis and treatment. This work demonstrates the ...
Journal of the American Medical Informatics Association : JAMIA
Mar 1, 2020
OBJECTIVE: We developed medExtractR, a natural language processing system to extract medication information from clinical notes. Using a targeted approach, medExtractR focuses on individual drugs to facilitate creation of medication-specific research...
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