Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Oct 23, 2024
An integral stage in typical digital pathology workflows involves deriving specific features from tiles extracted from a tessellated whole-slide image. Notably, various computer vision neural network architectures, particularly the ImageNet pretraine...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Oct 16, 2024
Lung cancer is one of the most prevalent and lethal cancers. To improve health outcomes while reducing health care burden, it becomes crucial to move toward early detection and cost-effective workflows. Currently, there is no method for the on-site r...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Sep 12, 2024
In the realm of health care, numerous generative and nongenerative artificial intelligence and machine learning (AI-ML) tools have been developed and deployed. Simultaneously, manufacturers of medical devices are leveraging AI-ML. However, the adopti...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Sep 10, 2024
Large B-cell lymphoma (LBCL) is a heterogeneous lymphoid malignancy in which MYC gene rearrangement (MYC-R) is associated with a poor prognosis, prompting the recommendation for more intensive treatment. MYC-R detection relies on fluorescence in situ...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Aug 13, 2024
Despite recent advances, the adoption of computer vision methods into clinical and commercial applications has been hampered by the limited availability of accurate ground truth tissue annotations required to train robust supervised models. Generatin...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Jul 26, 2024
The tissue diagnosis of adenocarcinoma and intraductal carcinoma of the prostate includes Gleason grading of tumor morphology on the hematoxylin and eosin stain and immunohistochemistry markers on the prostatic intraepithelial neoplasia-4 stain (CK5/...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Jul 17, 2024
An optimal approach to magnetic resonance imaging fusion targeted prostate biopsy (PBx) remains unclear (number of cores, intercore distance, Gleason grading [GG] principle). The aim of this study was to develop a precise pixel-wise segmentation diag...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Jul 16, 2024
The biopsy Gleason score is an important prognostic marker for prostate cancer patients. It is, however, subject to substantial variability among pathologists. Artificial intelligence (AI)-based algorithms employing deep learning have shown their abi...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Jul 15, 2024
Reducing recurrence following radical resection of colon cancer without overtreatment or undertreatment remains a challenge. Postoperative adjuvant chemotherapy (Adj) is currently administered based solely on pathologic TNM stage. However, prognosis ...
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc
Jun 17, 2024
Bone marrow aspiration (BMA) smear analysis is essential for diagnosis, treatment, and monitoring of a variety of benign and neoplastic hematological conditions. Currently, this analysis is performed by manual microscopy. We conducted a multicenter s...