Endometriosis (EMs) and recurrent miscarriage (RM) represent major reproductive health challenges. This study investigates the involvement of endothelial-mesenchymal transition (EndMT) in these conditions through integrative bioinformatics analysis, ...
Recurrent spontaneous abortion (RSA) represents a significant challenge in reproductive obstetrics, affecting approximately 5% of couples globally. Despite various treatments, the effectiveness of these interventions remains highly contentious. Emerg...
Recurrent pregnancy loss (RPL), which affects approximately 2.5% of reproductive-aged women, remains idiopathic in more than 50% of cases, necessitating mechanistic insights and biomarkers. Three RPL decidual tissue transcriptomic datasets (GSE113790...
BACKGROUND: Recurrent pregnancy loss (RPL), characterized by multiple miscarriages, remains a condition with unclear etiology, posing significant challenges for affected women and couples. This study aims to explore the underlying mechanisms of RPL, ...
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Dec 18, 2024
PURPOSE: This review aims to identify and analyze the risk factors associated with recurrent pregnancy loss (RPL) and to evaluate the effectiveness of various predictive models in estimating the risk of RPL. The review also explores recent advancemen...
OBJECTIVE: More and more studies have found that polycystic ovary syndrome (PCOS) is significantly associated with recurrent spontaneous abortion (RSA), but the specific mechanism is not yet clear.
It has been recognized that oxidative stress (OS) is implicated in the etiology of recurrent pregnancy loss (RPL), yet the biomarkers reflecting oxidative stress in association with RPL remain scarce. The dataset GSE165004 was retrieved from the Gene...
BACKGROUND: Recurrent pregnancy loss (RPL) frequently links to a prolonged endometrial receptivity (ER) window, leading to the implantation of non-viable embryos. Existing ER assessment methods face challenges in reliability and invasiveness. Radiomi...
RPL is a very debated condition, in which many issues concerning definition, etiological factors to investigate or therapies to apply are still controversial. ML could help clinicians to reach an objectiveness in RPL classification and access to care...
The Kaohsiung journal of medical sciences
Dec 20, 2016
A disintegrin-like and metalloproteinase domain with thrombospondin-type 1 motifs (ADAMTS) protein superfamily includes 19 secreted metalloproteases. Proteolytic substrates of ADAMTS enzymes have been linked to reproductive function. The aim of this ...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.