Humans segment experience into a nested series of discrete events, separated by neural state transitions that can be identified in fMRI data collected during passive movie viewing. Current neural state segmentation techniques manage the noisiness of ...
BACKGROUND: Inherited retinal diseases (IRDs) are the leading cause of blindness in young people in the UK. Despite significant improvements in genomics medicine, the diagnosis of these conditions remains challenging, and around 40% do not receive a ...
BACKGROUND: Major depressive disorder (MDD) is characterized by significant heterogeneity in treatment response, with inflammation hypothesized to play a role in its pathophysiology. Peripheral inflammatory biomarkers, such as the neutrophil-to-lymph...
Suicide represents an egregious threat to society despite major advancements in medicine, in part due to limited knowledge of the biological mechanisms of suicidal behavior. We apply a connectome predictive modeling machine learning approach to ident...
American journal of clinical pathology
Oct 4, 2025
OBJECTIVE: Prior studies have shown that pretransfusion medication is not effective in preventing allergic transfusion reactions (ATRs), but these studies did not consider the patient's history of ATR. This study evaluated whether pretransfusion anti...
The Journal of bone and joint surgery. American volume
Sep 17, 2025
BACKGROUND: Meniscal ramp lesions can impact knee stability, particularly when associated with anterior cruciate ligament (ACL) injuries. Although magnetic resonance imaging (MRI) is the primary diagnostic tool, its diagnostic accuracy remains subopt...
BACKGROUND: The aim is to develop prediction models by lifestyles indicators as well as socioeconomic status to predict the risk of depressive symptoms in adolescents, and to rank and explain these predictors.
The American journal of tropical medicine and hygiene
Sep 3, 2025
Dengue with warning signs (DWS) and severe dengue are significant public health concerns in tropical and subtropical regions globally. Accurate and timely differentiation between these clinical forms of dengue, although crucial, is often complex. In ...
BACKGROUND: Dengue, chikungunya, and Zika are diseases of major human concern. Differential diagnosis of these three diseases is complicated in children and adolescents due to overlapping clinical features (signs, symptoms, and complete blood count r...
Accurate prediction of skeletal changes during orthodontic treatment in growing patients remains challenging due to significant individual variability in craniofacial growth and treatment responses. Conventional methods, such as support vector regres...
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