AIMC Topic: Adolescent

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Machine learning models incorporating genotype and ancestry improve severe asthma risk prediction.

Scientific reports
This study proposes a novel machine learning (ML)-based stacking technique that integrates Single Nucleotide Polymorphisms (SNPs) and inferred local ancestry (LA) to improve predictive accuracy in clinical outcomes. Asthma, particularly severe asthma...

Distinct neuroimaging subtypes of ADHD among adolescents based on semi-supervised learning.

Translational psychiatry
Attention deficit hyperactivity disorder (ADHD) is a childhood-onset neurodevelopmental disorder diagnosed and subtyped solely based on clinical traits, which are prone to subjective judgment and lack of reliability. Also, the clinical subtyping does...

Application of Narrative and AI-Assisted Follow-Up After Voluntary Medical Male Circumcision: Multicenter, Double-Blind, Prospective, Randomized Controlled Trial.

Journal of medical Internet research
BACKGROUND: Postoperative anxiety following voluntary medical male circumcision (VMMC) poses a significant health challenge, with limited telemedicine access and inadequate communication compromising recovery and adherence. Narrative-based interventi...

Performance of the pediatric index of mortality (PIM-3) in a Moroccan PICU: challenges in resource-limited settings.

European journal of pediatrics
UNLABELLED: Prognostic scores such as the Pediatric Index of Mortality (PIM-3) are widely used to estimate mortality risk in PICUs, yet their performance in low- and middle-income countries (LMICs) remains uncertain. We aimed to evaluate the predicti...

Large language model as a clinical decision support tool in the initial management of critically ill children: a pilot evaluation.

European journal of pediatrics
UNLABELLED: Large language models (LLMs) like ChatGPT are being explored as clinical decision support tools, but their reliability in pediatric acute care remains uncertain. This pilot study assessed ChatGPT-4.0's performance in the early management ...

Multimodal prediction of psychotic-like experiences using elastic net modeling: external validation in a clinical sample.

Psychological medicine
BACKGROUND: Psychotic-like experiences (PLEs) are considered a subclinical component of psychosis continuum. Studies indicate that PLEs arise from multimodal factors, yet research comprehensively examining these factors together remains scarce. Using...

Acute myeloid leukemia risk stratification in younger and older patients through transcriptomic machine learning models.

Scientific reports
Acute Myeloid Leukemia (AML) is a genetically and clinically heterogeneous disease that can develop at any age. While AML incidence increases with age and distinct genetic alterations are observed in younger versus older patients, current classificat...

Modeling public trust in AI cognitive capabilities using statistical and machine learning approaches.

Scientific reports
As artificial intelligence (AI) systems increasingly perform cognitive functions, assessing public trust in these capabilities is critical. This study investigates the impact of age, gender, and familiarity with AI on confidence in AI's ability to ma...

Novel heterozygous mutation in KMT2B causing an unusual phenotypic presentation: a comprehensive clinical and bioinformatic analysis.

Molecular biology reports
BACKGROUND: KMT2B-related dystonia is a childhood-onset movement disorder. This study investigated a novel KMT2B gene variant using whole exome sequencing (WES) and bioinformatics analysis, and expanded the known clinical spectrum of KMT2B-related dy...

AI-Assisted 3D diagnosis of impacted maxillary canines: A validation study.

Clinical oral investigations
INTRODUCTION: This study aimed to validate an artificial intelligence (AI)-based automated image analysis for three-dimensional (3D) characterization of impacted canine position. In addition, it compared clinical treatment plans developed using conve...