AIMC Topic: Aged, 80 and over

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A non-invasive method for concurrent detection of early-stage women-specific cancers.

Scientific reports Feb 10, 2022
We integrated untargeted serum metabolomics using high-resolution mass spectrometry with data analysis using machine learning algorithms to accurately detect early stages of the women specific cancers of breast, endometrium, cervix, and ovary across ...
Metabolomics Genital Neoplasms, Female Women's Health Aged Aged, 80 and over Young Adult Adult Sensitivity and Specificity Breast Neoplasms Biomarkers, Tumor Middle Aged Mass Spectrometry Early Detection of Cancer Humans Machine Learning Data Analysis Female
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Factors associated with long-term survival in gemcitabine-concurrent proton radiotherapy for non-metastatic locally advanced pancreatic cancer: a single-center retrospective study.

Radiation oncology (London, England) Feb 10, 2022
BACKGROUND: Factors associated with long-term survival in gemcitabine-concurrent proton radiotherapy (GPT) for non-metastatic, locally advanced pancreatic cancer (LAPC) remain unclear. This study aimed to determine the factors associated with long-te...
Adult Pancreatic Neoplasms Humans Gemcitabine Survival Rate Neoplasm Staging Retrospective Studies Proton Therapy Male Combined Modality Therapy Female Radiation-Sensitizing Agents Middle Aged Antimetabolites, Antineoplastic Aged Time Factors Deoxycytidine Aged, 80 and over
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Assessment of medical management in Coronary Type 2 Diabetic patients with previous percutaneous coronary intervention in Spain: A retrospective analysis of electronic health records using Natural Language Processing.

PloS one Feb 10, 2022
INTRODUCTION AND OBJECTIVES: Patients with type 2 diabetes (T2D) and stable coronary artery disease (CAD) previously revascularized with percutaneous coronary intervention (PCI) are at high risk of recurrent ischemic events. We aimed to provide real-...
Spain Diabetes Mellitus, Type 2 Natural Language Processing Percutaneous Coronary Intervention Coronary Artery Disease Myocardial Infarction Female Aged Aged, 80 and over Male Middle Aged Humans Retrospective Studies Electronic Health Records
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Classifying neovascular age-related macular degeneration with a deep convolutional neural network based on optical coherence tomography images.

Scientific reports Feb 9, 2022
Neovascular age-related macular degeneration (nAMD) is among the main causes of visual impairment worldwide. We built a deep learning model to distinguish the subtypes of nAMD using spectral domain optical coherence tomography (SD-OCT) images. Data f...
Female Aged Aged, 80 and over Male Middle Aged Humans Computer Simulation Diagnostic Techniques, Ophthalmological Ophthalmologists Deep Learning Tomography, Optical Coherence Macular Degeneration Neovascularization, Pathologic Pattern Recognition, Automated
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A joint convolutional-recurrent neural network with an attention mechanism for detecting intracranial hemorrhage on noncontrast head CT.

Scientific reports Feb 8, 2022
To investigate the performance of a joint convolutional neural networks-recurrent neural networks (CNN-RNN) using an attention mechanism in identifying and classifying intracranial hemorrhage (ICH) on a large multi-center dataset; to test its perform...
Humans Prospective Studies Retrospective Studies Emergency Service, Hospital Adult Intracranial Hemorrhage, Traumatic Male Tomography, X-Ray Computed Middle Aged Female Deep Learning Aged Adolescent Aged, 80 and over Young Adult
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Deep learning tools for the cancer clinic: an open-source framework with head and neck contour validation.

Radiation oncology (London, England) Feb 8, 2022
BACKGROUND: With the rapid growth of deep learning research for medical applications comes the need for clinical personnel to be comfortable and familiar with these techniques. Taking a proven approach, we developed a straightforward open-source fram...
Deep Learning Image Processing, Computer-Assisted Head and Neck Neoplasms Humans Female Neural Networks, Computer Aged Tomography, X-Ray Computed Aged, 80 and over Male Middle Aged
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Inferring protein expression changes from mRNA in Alzheimer's dementia using deep neural networks.

Nature communications Feb 3, 2022
Identifying the molecular systems and proteins that modify the progression of Alzheimer's disease and related dementias (ADRD) is central to drug target selection. However, discordance between mRNA and protein abundance, and the scarcity of proteomic...
Brain Female Aged Aged, 80 and over Male Humans Neural Networks, Computer RNA, Messenger Proteomics Proteome Mass Spectrometry Alzheimer Disease Protein Biosynthesis Transcriptome Deep Learning Cognitive Dysfunction Dementia RNA-Seq
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Distribution Characteristics of ST-Segment Elevation Myocardial Infarction and Non-ST-Segment Elevation Myocardial Infarction Culprit Lesion in Acute Myocardial Infarction Patients Based on Coronary Angiography Diagnosis.

Computational and mathematical methods in medicine Feb 2, 2022
This research was aimed at exploring the application value of coronary angiography (CAG) based on a convolutional neural network algorithm in analyzing the distribution characteristics of ST-segment elevation myocardial infarction (STEMI) and non-ST-...
Male Middle Aged Computational Biology Electrocardiography Coronary Vessels Humans Non-ST Elevated Myocardial Infarction Diagnosis, Differential Angiography, Digital Subtraction Algorithms Neural Networks, Computer ST Elevation Myocardial Infarction Female Coronary Angiography Aged Myocardial Infarction Aged, 80 and over Early Diagnosis Adult
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Propofol Anesthesia Depth Monitoring Based on Self-Attention and Residual Structure Convolutional Neural Network.

Computational and mathematical methods in medicine Jan 29, 2022
METHODS: We compare nine index values, select CNN+EEG, which has good correlation with BIS index, as an anesthesia state observation index to identify the parameters of the model, and establish a model based on self-attention and dual resistructure c...
Humans Neural Networks, Computer Algorithms Aged Aged, 80 and over Young Adult Adult Male Middle Aged Anesthetics, Intravenous Deep Learning Attention Intraoperative Neurophysiological Monitoring Computational Biology Propofol Electroencephalography
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Multiple instance learning detects peripheral arterial disease from high-resolution color fundus photography.

Scientific reports Jan 26, 2022
Peripheral arterial disease (PAD) is caused by atherosclerosis and is a common disease of the elderly leading to excess morbidity and mortality. Early PAD diagnosis is important, as the only available causal therapy is addressing risk factors like sm...
Retinal Vessels Feasibility Studies Early Diagnosis Optic Disk Diagnostic Techniques, Ophthalmological Photography Female Aged Aged, 80 and over Humans Male Deep Learning Neural Networks, Computer Middle Aged ROC Curve Biomarkers Peripheral Arterial Disease Area Under Curve Fundus Oculi
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