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Alzheimer Disease

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A support vector machine-based approach to guide the selection of a pseudo-reference region for brain PET quantification.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism
A Support Vector Machine (SVM) based approach was developed to identify a pseudo-reference region for brain PET scans with the aim of reducing interscan and intersubject variability. By training a binary linear SVM classifier with PET datasets from t...

Knowledge-driven multi-graph convolutional network for brain network analysis and potential biomarker discovery.

Medical image analysis
In brain network analysis, individual-level data can provide biological features of individuals, while population-level data can provide demographic information of populations. However, existing methods mostly utilize either individual- or population...

A deep learning approach for non-invasive Alzheimer's monitoring using microwave radar data.

Neural networks : the official journal of the International Neural Network Society
Over 50 million people globally suffer from Alzheimer's disease (AD), emphasizing the need for efficient, early diagnostic tools. Traditional methods like Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) scans are expensive, bulky, and s...

Explainability of CNN-based Alzheimer's disease detection from online handwriting.

Scientific reports
With over 55 million people globally affected by dementia and nearly 10 million new cases reported annually, Alzheimer's disease is a prevalent and challenging neurodegenerative disorder. Despite significant advancements in machine learning technique...

3-1-3 Weight averaging technique-based performance evaluation of deep neural networks for Alzheimer's disease detection using structural MRI.

Biomedical physics & engineering express
Alzheimer's disease (AD) is a progressive neurological disorder. It is identified by the gradual shrinkage of the brain and the loss of brain cells. This leads to cognitive decline and impaired social functioning, making it a major contributor to dem...

Early diagnosis of Alzheimer's Disease based on multi-attention mechanism.

PloS one
Alzheimer's Disease is a neurodegenerative disorder, and one of its common and prominent early symptoms is language impairment. Therefore, early diagnosis of Alzheimer's Disease through speech and text information is of significant importance. Howeve...

Integrated Ultrasound-Enrichment and Machine Learning in Colorimetric Lateral Flow Assay for Accurate and Sensitive Clinical Alzheimer's Biomarker Diagnosis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
The colloidal gold nanoparticle (AuNP)-based colorimetric lateral flow assay (LFA) is one of the most promising analytical tools for point-of-care disease diagnosis. However, the low sensitivity and insufficient accuracy still limit its clinical appl...

Automated classification of Alzheimer's disease, mild cognitive impairment, and cognitively normal patients using 3D convolutional neural network and radiomic features from T1-weighted brain MRI: A comparative study on detection accuracy.

Clinical imaging
OBJECTIVES: Alzheimer's disease (AD) is a common neurodegenerative disorder that primarily affects older individuals. Due to its high incidence, an accurate and efficient stratification system could greatly aid in the clinical diagnosis and prognosis...

AI-driven innovations in Alzheimer's disease: Integrating early diagnosis, personalized treatment, and prognostic modelling.

Ageing research reviews
Alzheimer's disease (AD) presents a significant challenge in neurodegenerative research and clinical practice due to its complex etiology and progressive nature. The integration of artificial intelligence (AI) into the diagnosis, treatment, and progn...