IEEE transactions on neural networks and learning systems
Aug 3, 2022
Accurate prediction of clinical scores (of neuropsychological tests) based on noninvasive structural magnetic resonance imaging (MRI) helps understand the pathological stage of dementia (e.g., Alzheimer's disease (AD)) and forecast its progression. E...
OBJECTIVE: While the use of biomarkers for the detection of early and preclinical Alzheimer's Disease has become essential, the need to wait for over an hour after injection to obtain sufficient image quality can be challenging for patients with susp...
BMC medical informatics and decision making
Jul 7, 2022
BACKGROUND: Since no effective therapies exist for Alzheimer's disease (AD), prevention has become more critical through lifestyle status changes and interventions. Analyzing electronic health records (EHRs) of patients with AD can help us better und...
Worldwide, there are nearly 10 million new cases of dementia annually, of which Alzheimer's disease (AD) is the most common. New measures are needed to improve the diagnosis of individuals with cognitive impairment due to various etiologies. Here, we...
Currently there are no reliable biomarkers for early detection of Alzheimer's disease (AD) at the preclinical stage. This study assessed the pupil light reflex (PLR) for focal red and blue light stimuli in central and peripheral retina in 125 cogniti...
Alzheimer's Disease (AD) is an irreversible neurodegenerative disease that results in a progressive decline in cognitive abilities. Since AD starts several years before the onset of the symptoms, its early detection is challenging due to subtle chang...
Alzheimer's & dementia : the journal of the Alzheimer's Association
Jun 6, 2022
INTRODUCTION: To test the utility of the "A/T/N" system in the Chinese population, we study core Alzheimer's disease (AD) biomarkers in a newly established Chinese cohort.
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
Jun 2, 2022
PURPOSE: To validate our previously proposed method of quantifying amyloid-beta (Aβ) load using nonspecific (NS) estimates generated with convolutional neural networks (CNNs) using [F]Florbetapir scans from longitudinal and multicenter ADNI data.
Alzheimer's disease (AD) is the leading cause of dementia globally, with a growing morbidity burden that may exceed diagnosis and management capabilities. The situation worsens when AD patient fatalities are exposed to COVID-19. Because of difference...
Deep learning offers a powerful approach for analyzing hippocampal changes in Alzheimer's disease (AD) without relying on handcrafted features. Nevertheless, an input format needs to be selected to pass the image information to the neural network, wh...