AIMC Topic: Alzheimer Disease

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Quantitative Longitudinal Predictions of Alzheimer's Disease by Multi-Modal Predictive Learning.

Journal of Alzheimer's disease : JAD
BACKGROUND: Quantitatively predicting the progression of Alzheimer's disease (AD) in an individual on a continuous scale, such as the Alzheimer's Disease Assessment Scale-cognitive (ADAS-cog) scores, is informative for a personalized approach as oppo...

Analysis of Risk Factors in Dementia Through Machine Learning.

Journal of Alzheimer's disease : JAD
BACKGROUND: Sociodemographic data indicate the progressive increase in life expectancy and the prevalence of Alzheimer's disease (AD). AD is raised as one of the greatest public health problems. Its etiology is twofold: on the one hand, non-modifiabl...

Machine Learning-Supported Analyses Improve Quantitative Histological Assessments of Amyloid-β Deposits and Activated Microglia.

Journal of Alzheimer's disease : JAD
BACKGROUND: Detailed pathology analysis and morphological quantification is tedious and prone to errors. Automatic image analysis can help to increase objectivity and reduce time. Here, we present the evaluation of the DeePathology STUDIO™ for automa...

Construction of MRI-Based Alzheimer's Disease Score Based on Efficient 3D Convolutional Neural Network: Comprehensive Validation on 7,902 Images from a Multi-Center Dataset.

Journal of Alzheimer's disease : JAD
BACKGROUND: In recent years, many convolutional neural networks (CNN) have been proposed for the classification of Alzheimer's disease. Due to memory constraints, many of the proposed CNNs work at a 2D slice-level or 3D patch-level.

Diagnosis of Alzheimer's Disease Based on Deeply-Fused Nets.

Combinatorial chemistry & high throughput screening
AIM AND OBJECTIVE: Fast and accurate diagnosis of Alzheimer's disease is very important for the care and further treatment of patients. Along with the development of deep learning, impressive progress has also been made in the automatic diagnosis of ...

DeepDicomSort: An Automatic Sorting Algorithm for Brain Magnetic Resonance Imaging Data.

Neuroinformatics
With the increasing size of datasets used in medical imaging research, the need for automated data curation is arising. One important data curation task is the structured organization of a dataset for preserving integrity and ensuring reusability. Th...

Reproducible Evaluation of Diffusion MRI Features for Automatic Classification of Patients with Alzheimer's Disease.

Neuroinformatics
Diffusion MRI is the modality of choice to study alterations of white matter. In past years, various works have used diffusion MRI for automatic classification of Alzheimer's disease. However, classification performance obtained with different approa...

A systematic literature review of automatic Alzheimer's disease detection from speech and language.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: In recent years numerous studies have achieved promising results in Alzheimer's Disease (AD) detection using automatic language processing. We systematically review these articles to understand the effectiveness of this approach, identify ...

Binary Classification of Alzheimer's Disease Using sMRI Imaging Modality and Deep Learning.

Journal of digital imaging
Alzheimer's disease (AD) is an irreversible devastative neurodegenerative disorder associated with progressive impairment of memory and cognitive functions. Its early diagnosis is crucial for the development of possible future treatment option(s). St...

Regularized Bagged Canonical Component Analysis for Multiclass Learning in Brain Imaging.

Neuroinformatics
A fundamental problem of supervised learning algorithms for brain imaging applications is that the number of features far exceeds the number of subjects. In this paper, we propose a combined feature selection and extraction approach for multiclass pr...