AIMC Topic: Anesthetics, Local

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Physicochemical stability of an admixture of lidocaine and ketamine in polypropylene syringe used in opioid-free anaesthesia.

European journal of hospital pharmacy : science and practice Oct 18, 2019
OBJECTIVES: Opioid-free anaesthesia is a treatment strategy of pain management based on the use of drugs such as lidocaine, ketamine and dexmedetomidine that do not interact significantly with opioid receptors. In particular, these drugs are used by ...
Drug Therapy, Combination Analgesics, Opioid Anesthesia Chromatography, High Pressure Liquid Humans Chemical Phenomena Syringes Ketamine Polypropylenes Lidocaine Drug Stability Anesthetics, Local Analgesics
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A Radical Proposition: Opioid-sparing Prostatectomy.

European urology focus Jun 21, 2019
Radical prostatectomy has largely become a procedure requiring a single day in the hospital with improving convalescence. Pre-operative counseling on perioperatively expectations including a discussion of pain management using non-opioid alternatives...
Anesthetics, Local Robotics Double-Blind Method Pain, Postoperative Humans Prostatectomy Male
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Local Infiltration Analgesia With Liposomal Bupivacaine Improves Early Outcomes After Total Knee Arthroplasty: 24-Hour Data From the PILLAR Study.

The Journal of arthroplasty Dec 25, 2018
BACKGROUND: Enhanced postoperative care pathways have shifted total knee arthroplasty (TKA) to outpatient and short-stay settings, placing greater emphasis on predischarge outcomes. In this study, we report prespecified secondary and tertiary end poi...
Anesthetics, Local Double-Blind Method Pain, Postoperative Bupivacaine Analgesics, Opioid Arthroplasty, Replacement, Knee Pain Management Analgesia Aged Aged, 80 and over Male Middle Aged Humans Female
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Investigating a Needle-Based Epidural Procedure in Obstetric Anesthesia.

AMIA ... Annual Symposium proceedings. AMIA Symposium Dec 5, 2018
This study investigates the safety and efficacy of a large-dose, needle-based epidural technique in obstetric anesthesia. The technique differs from a standard, catheter-based approach in that the anesthetic dose is administered through an epidural n...
Needles Task Performance and Analysis Humans Workflow Analgesia, Obstetrical Machine Learning Hypotension Pregnancy Anesthesia, Obstetrical Female Anesthesia, Epidural Anesthetics, Local
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Use of Topical Lidocaine Gel Plus Paracervical Blockade vs. Paracervical Blockade Alone for Pain Management During Manual Vacuum Aspiration: ADouble-Blind, Randomized, Placebo-Controlled Trial.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC Oct 26, 2018
OBJECTIVE: To evaluate if the use of lidocaine gel applied to the cervix prior to manual vacuum aspiration (MVA) in addition to paracervical blockade is useful in reducing the level of pain associated with the procedure.
Pain Management Humans Cervix Uteri Gels Prospective Studies Anesthesia, Obstetrical Lidocaine Pregnancy Vacuum Curettage Anesthetics, Local Female Double-Blind Method
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Neurotoxicity of intraneural injection of bupivacaine liposome injectable suspension versus bupivacaine hydrochloride in a porcine model.

Veterinary anaesthesia and analgesia Oct 11, 2018
OBJECTIVE: To test whether neurotoxic effects of a bupivacaine liposome injectable suspension differ from those of a standard formulation of bupivacaine hydrochloride (HCl) after intraneural injection into the sciatic nerves in pigs.
Liposomes Drug Compounding Random Allocation Models, Animal Anesthetics, Local Prospective Studies Bupivacaine Female Sciatic Nerve Animals Injections Male Swine
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Effects of hyaluronidase on ropivacaine or bupivacaine regional anaesthesia of the canine pelvic limb.

Veterinary anaesthesia and analgesia Sep 28, 2018
OBJECTIVE: To determine the effect of hyaluronidase on time to onset and offset of anaesthesia in ropivacaine or bupivacaine femoral-ischiatic nerve blocks.
Female Random Allocation Femoral Nerve Hindlimb Hyaluronoglucosaminidase Anesthetics, Local Pain Measurement Bupivacaine Ropivacaine Dogs Animals Male Nerve Block Treatment Outcome
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Effect of Pulsed Radiofrequency Treatment on the Thoracic Medial Branch for Managing Chronic Thoracic Facet Joint Pain Refractory to Medial Branch Block with Local Anesthetics.

World neurosurgery Dec 30, 2017
OBJECTIVE: To evaluate the effect of pulsed radiofrequency (PRF) stimulation of the thoracic medial branch of the dorsal ramus in patients with chronic thoracic facet joint (TFJ) pain who were refractory to medial branch block (MBB).
Drug Resistance Pulsed Radiofrequency Treatment Zygapophyseal Joint Treatment Outcome Anesthetics, Local Pain Measurement Back Pain Humans Prospective Studies Female Aged Adult Male Middle Aged Thoracic Vertebrae Nerve Block
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A randomized comparison between interscalene and combined infraclavicular-suprascapular blocks for arthroscopic shoulder surgery.

Canadian journal of anaesthesia = Journal canadien d'anesthesie Dec 19, 2017
BACKGROUND: This randomized trial aimed to evaluate combined infraclavicular-suprascapular blocks (ICB-SSBs) as a diaphragm-sparing alternative to interscalene blocks (ISBs) for arthroscopic shoulder surgery. We hypothesized that ICB-SSB would provid...
Humans Female Anesthetics, Local Ultrasonography, Interventional Pain, Postoperative Analgesics, Opioid Morphine Aged Adult Male Middle Aged Shoulder Joint Arthroscopy Brachial Plexus Block Epinephrine Levobupivacaine
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Effectiveness of continuous wound infusion of local anesthetics after abdominal surgeries.

The Journal of surgical research Dec 29, 2016
BACKGROUND: To assess the effectiveness of continuous preperitoneal wound infusion of local anesthetic drug bupivacaine in providing pain relief, reducing opioid consumption, and enhancing postoperative recovery.
Bupivacaine Analgesics, Opioid Morphine Drug Therapy, Combination Drug Administration Schedule Anesthetics, Local Pain Measurement Double-Blind Method Pain, Postoperative Infusions, Parenteral Infusions, Intralesional Middle Aged Humans Aged, 80 and over Adolescent Young Adult Prospective Studies Abdomen Adult Female Treatment Outcome Male Aged Follow-Up Studies
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