AIMC Topic: Animals
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Structural modification strategies for ferritin nanoparticles and their applications in biomedicine: a narrative review.
Nanoscale
Jul 31, 2025
Ferritin is an iron-storage protein that naturally self-assembles into a hollow spherical particle consisting of 24 identical subunits, and it serves a central role in iron metabolism. Ferritin's favorable drug-loading capacity, biocompatibility, int...
Advances in mass spectrometry of lipids for the investigation of Niemann-pick type C disease.
Lipids in health and disease
Jul 30, 2025
Niemann-Pick type C (NPC) disease is a devastating, fatal, neurodegenerative disease and a form of lysosomal storage disorder. It is caused by mutations in either NPC1 or NPC2 genes, leading to the accumulation of cholesterol and other lipids in the ...
High-Resolution Ultrasound Data for AI-Based Segmentation in Mouse Brain Tumor.
Scientific data
Jul 30, 2025
Glioblastoma multiforme (GBM) is the most aggressive type of brain cancer, making effective treatments essential to improve patient survival. To advance the understanding of GBM and develop more effective therapies, preclinical studies commonly use m...
Spiking dynamics of individual neurons reflect changes in the structure and function of neuronal networks.
Nature communications
Jul 30, 2025
Brain networks exhibit diverse topological structures to adapt and support brain functions. The changes in neuronal network architecture can lead to alterations in neuronal spiking activity, yet how individual neuronal behavior reflects network struc...
AI search, physician removal: Bronchoscopy robot bridges collaboration in foreign body aspiration.
Science robotics
Jul 30, 2025
Bronchial foreign body aspiration is a life-threatening condition with a high incidence across diverse populations, requiring urgent diagnosis and treatment. However, the limited availability of skilled practitioners and advanced medical equipment in...
Integrative transcriptomics and metabolomics reveal neuroendocrine-lipid crosstalk and adenosine signaling in broiler under heat stress.
BMC genomics
Jul 29, 2025
BACKGROUND: Heat stress (HS) is a significant challenge in poultry, negatively impacting feed efficiency and survival. These adaptive responses could lead to disrupted lipid metabolism, impaired immunity, and neural damage. We hypothesized that the n...
PuMA: PubMed gene/cell type-relation Atlas.
BMC bioinformatics
Jul 29, 2025
BACKGROUND: Rapid extraction and visualization of cell-specific gene expression is important for automatic cell type annotation, e.g. in single cell analysis. There is an emerging field in which tools such as curated databases or machine learning met...
Nondestructive freshness recognition of chicken breast meat based on deep learning.
Scientific reports
Jul 29, 2025
Identifying chicken breast freshness is an important component of poultry food safety. Traditional methods for chicken breast freshness recognition suffer from issues such as high cost, difficulty in recognition, and low efficiency. In this study, th...
Candesartan Mitigates Perioperative Neurocognitive Disorders by Modulating Hypertension-Linked Neuroinflammatory Factor.
Neurochemical research
Jul 29, 2025
Perioperative neurocognitive disorders (PND) are linked to neuroinflammation, a key factor in hypertension, but their causal relationship is underexplored. This study aims to investigate whether hypertension is a risk factor for PND, identify related...
CPN2 alleviates cryptorchidism by inhibiting the NF-κB pathway and regulating immune responses.
Autoimmunity
Jul 28, 2025
Cryptorchidism, a common male reproductive disorder characterized by undescended testes, is associated with infertility and increased cancer risk. While its etiology remains incompletely understood, accumulating evidence suggests that immune-inflamma...
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