Genomics, proteomics & bioinformatics
Jan 11, 2019
As a newly-identified protein post-translational modification, malonylation is involved in a variety of biological functions. Recognizing malonylation sites in substrates represents an initial but crucial step in elucidating the molecular mechanisms ...
IEEE/ACM transactions on computational biology and bioinformatics
Jan 10, 2019
Most proposed methods for TF-binding site (TFBS) predictions only use low order dependencies for predictions due to the lack of efficient methods to extract higher order dependencies. In this work, we first propose a novel method to extract higher or...
BACKGROUND: The Single Port Orifice Robotic Technology (SPORT) Surgical System by Titan Medical Inc. is designed to overcome the inherent challenges of minimally invasive single-access procedures. The aim of this preclinical study was to evaluate the...
BACKGROUND: The efficiency of drug development defined as a number of successfully launched new pharmaceuticals normalized by financial investments has significantly declined. Nonetheless, recent advances in high-throughput experimental techniques an...
One of the most popular techniques in zebrafish research is microinjection. This is a rapid and efficient way to genetically manipulate early developing embryos, and to introduce microbes, chemical compounds, nanoparticles or tracers at larval stages...
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Jan 4, 2019
Rodents engage in social communication through a rich repertoire of ultrasonic vocalizations (USVs). Recording and analysis of USVs has broad utility during diverse behavioral tests and can be performed noninvasively in almost any rodent behavioral m...
Fish embryo models are widely used as screening tools to assess the efficacy and/or toxicity of chemicals. This assessment involves the analysis of embryo morphological abnormalities. In this article, we propose a multi-scale pipeline to allow automa...
Database : the journal of biological databases and curation
Jan 1, 2019
High-throughput studies constitute an essential and valued source of information for researchers. However, high-throughput experimental workflows are often complex, with multiple data sets that may contain large numbers of false positives. The repres...
Glyphosate is one of the most widely used herbicides in the United States, which has led to its ubiquitous occurrence in food and water and regular detection in human urine at concentrations of 1-10 μg/L. Data pertaining to health risks arising from ...
This work investigated the thermophilic (55 °C) co-digestion performance both in batch and continuous mode operation. The biochemical methane potentials of L. digitata and cattle manure were 308 ± 24 and 203 ± 33 mL CH/g VS, respectively. The optimum...
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