Available classification tools and risk factors predicting bleeding events in elderly patients after mechanical valve replacement may not be suitable in Asian populations. Thus, we aimed to identify an accurate model for predicting bleeding in elderl...
Se pu = Chinese journal of chromatography
Oct 8, 2020
Heparin is composed of a highly sulfated linear saccharide and is widely used as an anticoagulant. Low molecular weight heparins (LMWHs) are derived from the unfractionated heparin (UFH) by enzymatic or chemical degradation. LMWHs have largely replac...
European heart journal. Cardiovascular pharmacotherapy
Sep 1, 2020
AIMS: Most clinical risk stratification models are based on measurement at a single time-point rather than serial measurements. Artificial intelligence (AI) is able to predict one-dimensional outcomes from multi-dimensional datasets. Using data from ...
Geriatrie et psychologie neuropsychiatrie du vieillissement
Dec 1, 2019
Atrial fibrillation (AF) is common in the elderly. The treatment of this condition is based on anticoagulation to prevent stroke and systemic arterial embolism. Vitamin K antagonists (VKAs) have long been the only anticoagulants available for the man...
PURPOSE: Appropriate dosing of direct oral anticoagulants (DOACs) requires consideration of renal function. Discordance between commonly used estimated glomerular filtration rate (eGFR) and creatinine clearance (CrCl) might affect the dosing appropri...
Combinatorial chemistry & high throughput screening
Jan 1, 2018
BACKGROUND: Thrombin is the central protease of the vertebrate blood coagulation cascade, which is closely related to cardiovascular diseases. The inhibitory constant Ki is the most significant property of thrombin inhibitors.
Studies in health technology and informatics
Jan 1, 2018
In this paper, we present a system that allows patients who require anticoagulation medicine an opportunity to independently manage their dosage concentration with the help of two machine learning algorithms. The basic idea is to predict the next dos...
Studies in health technology and informatics
Jan 1, 2017
Dividing patients into similar groups plays a significant role in implementing personalized care. Clinicians and researchers have been applying patient grouping techniques in disease phenotyping, risk stratification, and personalized medicine. Howeve...
Papillary fibroelastomas of the mitral chordae tendineae are rare, primary benign tumors. They are either incidentally diagnosed during echocardiography or discovered after transient ischemic attack, stroke, or myocardial infarction. Removal of papil...
The journal of extra-corporeal technology
Dec 1, 2015
We present a case of a patient with factor V Leiden with an antithrombin III activity of 67% who received a successful aortic valve replacement supported by cardiopulmonary bypass (CPB). A safe level of anticoagulation was achieved by monitoring acti...
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