BACKGROUND: The effect of renal impairment in patients who receive intravenous thrombolysis for acute ischemic stroke (AIS) is unclear. We aimed to determine the associations of renal impairment and clinical outcomes and any modification of the effec...
Luminescence : the journal of biological and chemical luminescence
40344502
In this study, we present a direct, sensitive, and green spectrofluorimetric approach for simultaneous measurement of bisoprolol fumarate (BSL) and amlodipine besylate (AMD) in their tablets and plasma. This approach measures the synchronized fluores...
PURPOSE: To develop machine learning (ML) and deep learning (DL) models to predict glaucoma surgical outcomes, including postoperative intraocular pressure, use of ocular antihypertensive medications, and need for repeat surgery.
BACKGROUND: High systolic blood pressure is one of the leading global risk factors for mortality, contributing significantly to cardiovascular diseases. Despite advances in treatment, a large proportion of patients with hypertension do not achieve op...
AIM: We aimed to identify the characteristics of patients with diabetes who can derive cognitive benefits from intensive blood pressure (BP) treatment using machine learning methods.
Food research international (Ottawa, Ont.)
39967093
Hypertension is a major global health concern, and there is a need for new antihypertensive agents derived from natural sources. This study aims to identify novel angiotensin I-converting enzyme (ACE) inhibitors from bioactive peptides derived from f...
Hypertension, often known as high blood pressure, is a major concern to millions of individuals globally. Recent studies have demonstrated the significant efficacy of naturally derived peptides in reducing blood pressure. Hypertension is one of the r...
The hypotensive side effects caused by drugs during their use have been a vexing issue. Recent studies have found that deep learning can effectively predict the biological activity of compounds by mining patterns and rules in the data, providing a po...
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
39957174
OBJECTIVE: To enhance the understanding of identifying personalized pharmacotherapy options in Traditional Chinese Medicine (TCM), and further support the registration of new TCM drugs.
Hypertension is a multifaceted cardiovascular disease, a significant risk factor for stroke, heart attack, heart failure, and renal damage. An essential phase in the drug development process is the exploration of effective bioanalytical approaches to...