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Comparative analysis of machine learning approaches to classify tumor mutation burden in lung adenocarcinoma using histopathology images.

Scientific reports Aug 16, 2021
Both histologic subtypes and tumor mutation burden (TMB) represent important biomarkers in lung cancer, with implications for patient prognosis and treatment decisions. Typically, TMB is evaluated by comprehensive genomic profiling but this requires ...
Adult Male Middle Aged Deep Learning ROC Curve Lung Neoplasms Staining and Labeling Carcinoma, Non-Small-Cell Lung Age Factors Area Under Curve Adenocarcinoma of Lung Humans Eosine Yellowish-(YS) Female Hematoxylin Aged Aged, 80 and over Mutation Coloring Agents Sex Factors Datasets as Topic Smoking
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Automatic detection of pathological myopia using machine learning.

Scientific reports Aug 16, 2021
Pathological myopia is a severe case of myopia, i.e., nearsightedness. Pathological myopia is also known as degenerative myopia because it ultimately leads to blindness. In pathological myopia, certain myopia-specific pathologies occur at the eye's p...
ROC Curve Image Processing, Computer-Assisted Models, Neurological Predictive Value of Tests Area Under Curve Datasets as Topic Myopia, Degenerative Humans Deep Learning
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Radiomics machine learning study with a small sample size: Single random training-test set split may lead to unreliable results.

PloS one Aug 12, 2021
This study aims to determine how randomly splitting a dataset into training and test sets affects the estimated performance of a machine learning model and its gap from the test performance under different conditions, using real-world brain tumor rad...
Image Processing, Computer-Assisted Humans Magnetic Resonance Imaging Machine Learning Glioblastoma Retrospective Studies Area Under Curve Brain Neoplasms
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Use of machine learning method on automatic classification of motor subtype of Parkinson's disease based on multilevel indices of rs-fMRI.

Parkinsonism & related disorders Aug 11, 2021
OBJECTIVE: This study aimed to develop an automatic classifier to distinguish different motor subtypes of Parkinson's disease (PD) based on multilevel indices of resting-state functional magnetic resonance imaging (rs-fMRI).
Area Under Curve Postural Balance Gait Rest Statistics, Nonparametric Multilevel Analysis Middle Aged ROC Curve Support Vector Machine Magnetic Resonance Imaging Parkinson Disease Female Aged Sensitivity and Specificity Male Humans Machine Learning Brain
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Machine learning model for early prediction of acute kidney injury (AKI) in pediatric critical care.

Critical care (London, England) Aug 10, 2021
BACKGROUND: Acute kidney injury (AKI) in pediatric critical care patients is diagnosed using elevated serum creatinine, which occurs only after kidney impairment. There are no treatments other than supportive care for AKI once it has developed, so it...
Infant Severity of Illness Index Adolescent Cohort Studies Child, Preschool Female Infant, Newborn Young Adult Male Pediatrics Child Intensive Care Units, Pediatric ROC Curve Area Under Curve Critical Care Humans Machine Learning Computer Simulation Acute Kidney Injury
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Attention-based deep learning system for automated diagnoses of age-related macular degeneration in optical coherence tomography images.

Medical physics Aug 9, 2021
PURPOSE: The progression of age-related macular degeneration (AMD) is critical to treatment decisions in clinical practice. The disease can be classified into four categories namely, drusen, inactive choroidal neovascularization (CNV), active CNV, an...
Deep Learning Area Under Curve Tomography, Optical Coherence Retina Macular Degeneration Humans
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Deep graph neural network-based prediction of acute suicidal ideation in young adults.

Scientific reports Aug 4, 2021
Precise remote evaluation of both suicide risk and psychiatric disorders is critical for suicide prevention as well as for psychiatric well-being. Using questionnaires is an alternative to labor-intensive diagnostic interviews in a large general popu...
Suicide, Attempted Psychiatric Status Rating Scales Depression Resilience, Psychological Surveys and Questionnaires Young Adult Adult Sensitivity and Specificity Male Anxiety Humans Mental Disorders Adolescent Neural Networks, Computer Prognosis Suicidal Ideation Republic of Korea Area Under Curve Female Self Concept Risk Factors
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Differentiation of Active Corneal Infections from Healed Scars Using Deep Learning.

Ophthalmology Aug 2, 2021
PURPOSE: To develop and evaluate an automated, portable algorithm to differentiate active corneal ulcers from healed scars using only external photographs.
Humans Algorithms Retrospective Studies Sensitivity and Specificity Slit Lamp Microscopy Corneal Ulcer Eye Infections, Fungal Area Under Curve Deep Learning Cicatrix ROC Curve False Positive Reactions Wound Healing Eye Infections, Bacterial Predictive Value of Tests Photography
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Short- and long-term mortality prediction after an acute ST-elevation myocardial infarction (STEMI) in Asians: A machine learning approach.

PloS one Aug 2, 2021
BACKGROUND: Conventional risk score for predicting short and long-term mortality following an ST-segment elevation myocardial infarction (STEMI) is often not population specific.
ST Elevation Myocardial Infarction Thrombosis Asian People Machine Learning Middle Aged Humans Female Time Factors Reproducibility of Results Hospital Mortality Risk Factors ROC Curve Male Area Under Curve
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Multimodal Machine Learning Using Visual Fields and Peripapillary Circular OCT Scans in Detection of Glaucomatous Optic Neuropathy.

Ophthalmology Jul 30, 2021
PURPOSE: To develop and validate a multimodal artificial intelligence algorithm, FusionNet, using the pattern deviation probability plots from visual field (VF) reports and circular peripapillary OCT scans to detect glaucomatous optic neuropathy (GON...
Machine Learning Glaucoma, Open-Angle Algorithms Female Retinal Ganglion Cells Vision Disorders Aged Visual Fields Humans Multimodal Imaging Adult Visual Field Tests Area Under Curve Optic Nerve Diseases Cross-Sectional Studies Tomography, Optical Coherence Intraocular Pressure Nerve Fibers Male Middle Aged ROC Curve
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