AIMC Topic: Arthritis, Rheumatoid

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A reliable time-series method for predicting arthritic disease outcomes: New step from regression toward a nonlinear artificial intelligence method.

Computer methods and programs in biomedicine Jan 9, 2020
BACKGROUND AND OBJECTIVE: The interrupted time-series (ITS) concept is performed using linear regression to evaluate the impact of policy changes in public health at a specific time. Objectives of this study were to verify, with an artificial intelli...
Humans Artificial Intelligence Research Design Incidence Arthroplasty, Replacement, Hip Hip Knee Interrupted Time Series Analysis Arthritis, Rheumatoid Outcome Assessment, Health Care Arthroplasty, Replacement, Knee Linear Models
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Mitochondrial dysfunction in rheumatoid arthritis: A comprehensive analysis by integrating gene expression, protein-protein interactions and gene ontology data.

PloS one Nov 8, 2019
Several studies have reported mitochondrial dysfunction in rheumatoid arthritis (RA). Many nuclear DNA (nDNA) encoded proteins translocate to mitochondria, but their participation in the dysfunction of this cell organelle during RA is quite unclear. ...
Arthritis, Rheumatoid Reactive Oxygen Species Humans Gene Ontology Models, Biological Gene Expression Profiling Mitochondrial Proteins Inflammation Protein Interaction Maps Oxidative Phosphorylation Mitochondria Synovial Membrane Gene Expression Regulation Apoptosis
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Machine Learning to Predict Anti-Tumor Necrosis Factor Drug Responses of Rheumatoid Arthritis Patients by Integrating Clinical and Genetic Markers.

Arthritis & rheumatology (Hoboken, N.J.) Nov 4, 2019
OBJECTIVE: Accurate prediction of treatment responses in rheumatoid arthritis (RA) patients can provide valuable information on effective drug selection. Anti-tumor necrosis factor (anti-TNF) drugs are an important second-line treatment after methotr...
Humans Machine Learning Tumor Necrosis Factor-alpha Antirheumatic Agents Treatment Outcome Normal Distribution Regression Analysis Middle Aged Etanercept Predictive Value of Tests Certolizumab Pegol Severity of Illness Index Infliximab Female Genetic Markers Arthritis, Rheumatoid Reproducibility of Results Methotrexate Polymorphism, Single Nucleotide Male Adalimumab Outcome Assessment, Health Care
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Automatic localization of anatomical regions in medical ultrasound images of rheumatoid arthritis using deep learning.

Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine Apr 24, 2019
The pace of population aging is growing faster worldwide. The quality of life of the aging population is mostly affected by rheumatic diseases. With the increasing rate of rheumatoid arthritis in the aging population, technological advances in the fi...
Humans Automation Deep Learning Ultrasonography Image Processing, Computer-Assisted Arthritis, Rheumatoid
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Automated feature selection of predictors in electronic medical records data.

Biometrics Apr 2, 2019
The use of Electronic Health Records (EHR) for translational research can be challenging due to difficulty in extracting accurate disease phenotype data. Historically, EHR algorithms for annotating phenotypes have been either rule-based or trained wi...
Natural Language Processing Translational Research, Biomedical Supervised Machine Learning Arthritis, Rheumatoid Logistic Models Cluster Analysis Humans Machine Learning Algorithms Phenotype Electronic Health Records
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Neural networks for automatic scoring of arthritis disease activity on ultrasound images.

RMD open Mar 30, 2019
BACKGROUND: The development of standardised methods for ultrasound (US) scanning and evaluation of synovitis activity by the OMERACT-EULAR Synovitis Scoring (OESS) system is a major step forward in the use of US in the diagnosis and monitoring of pat...
Case-Control Studies Deep Learning Ultrasonography Arthritis, Rheumatoid Neural Networks, Computer Humans Ultrasonography, Doppler Artificial Intelligence Severity of Illness Index Arthritis Synovitis
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Detection of rheumatoid arthritis from hand radiographs using a convolutional neural network.

Clinical rheumatology Mar 8, 2019
INTRODUCTION: Plain hand radiographs are the first-line and most commonly used imaging methods for diagnosis or differential diagnosis of rheumatoid arthritis (RA) and for monitoring disease activity. In this study, we used plain hand radiographs and...
Arthritis, Rheumatoid Radiography Hand Humans Neural Networks, Computer Sensitivity and Specificity
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Analysis of differentially expressed genes in rheumatoid arthritis and osteoarthritis by integrated microarray analysis.

Journal of cellular biochemistry Mar 4, 2019
BACKGROUND: Rheumatoid arthritis (RA) and osteoarthritis (OA) were two major types of joint diseases. This study aimed to explore the mechanism underlying OA and RA and analyze their difference by integrated analysis of multiple gene expression data ...
Oligonucleotide Array Sequence Analysis Oxidative Phosphorylation Inhibitor of Apoptosis Proteins Gene Expression Regulation Chemokines Ubiquitin-Protein Ligases Gene Ontology Signal Transduction Synovial Membrane Osteoarthritis Humans Gene Expression Profiling Protein Interaction Maps Gene Regulatory Networks Arthritis, Rheumatoid
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Assessment of a Deep Learning Model Based on Electronic Health Record Data to Forecast Clinical Outcomes in Patients With Rheumatoid Arthritis.

JAMA network open Mar 1, 2019
IMPORTANCE: Knowing the future condition of a patient would enable a physician to customize current therapeutic options to prevent disease worsening, but predicting that future condition requires sophisticated modeling and information. If artificial ...
Humans Forecasting Prognosis Electronic Health Records Female Aged Adult Male Arthritis, Rheumatoid Middle Aged Diagnosis, Computer-Assisted Deep Learning Cohort Studies
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Rheumatoid Arthritis: Atherosclerosis Imaging and Cardiovascular Risk Assessment Using Machine and Deep Learning-Based Tissue Characterization.

Current atherosclerosis reports Jan 25, 2019
PURPOSE OF THE REVIEW: Rheumatoid arthritis (RA) is a chronic, autoimmune disease which may result in a higher risk of cardiovascular (CV) events and stroke. Tissue characterization and risk stratification of patients with rheumatoid arthritis are a ...
Atherosclerosis Risk Factors Carotid Arteries Risk Assessment Plaque, Atherosclerotic Deep Learning Carotid Artery Diseases Humans Ultrasonography Arthritis, Rheumatoid Inflammation Tomography, Optical Coherence
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