AIMC Topic: Automation, Laboratory

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A versatile and low-cost open source pipetting robot for automation of toxicological and ecotoxicological bioassays.

PloS one
In the past decades, bioassays and whole-organism bioassay have become important tools not only in compliance testing of industrial chemicals and plant protection products, but also in the monitoring of environmental quality. With few exceptions, suc...

Automated histological classification of whole-slide images of gastric biopsy specimens.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association
BACKGROUND: Automated image analysis has been developed currently in the field of surgical pathology. The aim of the present study was to evaluate the classification accuracy of the e-Pathologist image analysis software.

Automated analysis of brain activity for seizure detection in zebrafish models of epilepsy.

Journal of neuroscience methods
BACKGROUND: Epilepsy is a chronic neurological condition, with over 30% of cases unresponsive to treatment. Zebrafish larvae show great potential to serve as an animal model of epilepsy in drug discovery. Thanks to their high fecundity and relatively...

Liquid-handling Lego robots and experiments for STEM education and research.

PLoS biology
Liquid-handling robots have many applications for biotechnology and the life sciences, with increasing impact on everyday life. While playful robotics such as Lego Mindstorms significantly support education initiatives in mechatronics and programming...

MRF-ANN: a machine learning approach for automated ER scoring of breast cancer immunohistochemical images.

Journal of microscopy
Molecular pathology, especially immunohistochemistry, plays an important role in evaluating hormone receptor status along with diagnosis of breast cancer. Time-consumption and inter-/intraobserver variability are major hindrances for evaluating the r...

High-throughput transformation of Saccharomyces cerevisiae using liquid handling robots.

PloS one
Saccharomyces cerevisiae (budding yeast) is a powerful eukaryotic model organism ideally suited to high-throughput genetic analyses, which time and again has yielded insights that further our understanding of cell biology processes conserved in human...

New Capabilities of EvoBot: A Modular, Open-Source Liquid-Handling Robot.

SLAS technology
We introduce a robot developed to perform feedback-based experiments, such as droplet experiments, a common type of experiments in artificial chemical life research. These experiments are particularly well suited for automation because they often str...

Artificial Neural Network for Total Laboratory Automation to Improve the Management of Sample Dilution.

SLAS technology
Diluting a sample to obtain a measure within the analytical range is a common task in clinical laboratories. However, for urgent samples, it can cause delays in test reporting, which can put patients' safety at risk. The aim of this work is to show a...

Vision-based Nano Robotic System for High-throughput Non-embedded Cell Cutting.

Scientific reports
Cell cutting is a significant task in biology study, but the highly productive non-embedded cell cutting is still a big challenge for current techniques. This paper proposes a vision-based nano robotic system and then realizes automatic non-embedded ...