AIMC Topic: Bacteria

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Predicting biomass conversion and COD removal in wastewater treatment by phototrophic bacteria with interpretable machine learning.

Journal of environmental management
Photosynthetic bacteria (PSB) excel in wastewater treatment by removing pollutants and generating biomass but are challenging to optimize due to complex operational and environmental interactions. Neural Ordinary Differential Equations, Elastic Net, ...

Automatic visual detection of activated sludge microorganisms based on microscopic phase contrast image optimisation and deep learning.

Journal of microscopy
The types and quantities of microorganisms in activated sludge are directly related to the stability and efficiency of sewage treatment systems. This paper proposes a sludge microorganism detection method based on microscopic phase contrast image opt...

Robotic versus manual disinfection of global priority pathogens at COVID-19-dedicated hospitals.

American journal of infection control
BACKGROUND: Twelve bacterial families identified as global priority pathogens (GPPs) pose the greatest threat to human health due to declining antibiotic efficacy. Robotics, a swift and contactless tool for disinfecting hospital surfaces, was sought ...

Bacteria Flagella-Mimicking Polymer Multilayer Magnetic Microrobots.

Small methods
Mass production of biomedical microrobots demands expensive and complex preparation techniques and versatile biocompatible materials. Learning from natural bacteria flagella, the study demonstrates a magnetic polymer multilayer cylindrical microrobot...

CAM/TMA-DPH as a promising alternative to SYTO9/PI for cell viability assessment in bacterial biofilms.

Frontiers in cellular and infection microbiology
INTRODUCTION: Accurately assessing biofilm viability is essential for evaluating both biofilm formation and the efficacy of antibacterial treatments. Traditional SYTO9 and propidium iodide (PI) live/dead staining in biofilm viability assays often ace...

Explainable deep learning and virtual evolution identifies antimicrobial peptides with activity against multidrug-resistant human pathogens.

Nature microbiology
Artificial intelligence (AI) is a promising approach to identify new antimicrobial compounds in diverse microbial species. Here we developed an AI-based, explainable deep learning model, EvoGradient, that predicts the potency of antimicrobial peptide...

Bacterial Wastewater-Based Epidemiology Using Surface-Enhanced Raman Spectroscopy and Machine Learning.

Nano letters
Although wastewater-based epidemiology has been used extensively for the surveillance of viral diseases, it has not been used to a similar extent for bacterial diseases. This is in part owing to difficulties in distinguishing pathogenic from nonpatho...

Clinical evaluation of a multiplex droplet digital PCR for diagnosing suspected bloodstream infections: a prospective study.

Frontiers in cellular and infection microbiology
BACKGROUND: Though droplet digital PCR (ddPCR) has emerged as a promising tool for early pathogen detection in bloodstream infections (BSIs), more studies are needed to support its clinical application widely due to different ddPCR platforms with dis...

Virtual Gram staining of label-free bacteria using dark-field microscopy and deep learning.

Science advances
Gram staining has been a frequently used staining protocol in microbiology. It is vulnerable to staining artifacts due to, e.g., operator errors and chemical variations. Here, we introduce virtual Gram staining of label-free bacteria using a trained ...

Open-set deep learning-enabled single-cell Raman spectroscopy for rapid identification of airborne pathogens in real-world environments.

Science advances
Pathogenic bioaerosols are critical for outbreaks of airborne disease; however, rapidly and accurately identifying pathogens directly from complex air environments remains highly challenging. We present an advanced method that combines open-set deep ...