Journal of computer-aided molecular design
Jan 20, 2020
Machine learning methods may have the potential to significantly accelerate drug discovery. However, the increasing rate of new methodological approaches being published in the literature raises the fundamental question of how models should be benchm...
Infections have become the major cause of morbidity and mortality among patients with chronic lymphocytic leukemia (CLL) due to immune dysfunction and cytotoxic CLL treatment. Yet, predictive models for infection are missing. In this work, we develop...
Coronary artery disease (CAD) is the leading global cause of mortality and has substantial heritability with a polygenic architecture. Recent approaches of risk prediction were based on polygenic risk scores (PRS) not taking possible nonlinear effect...
Medical & biological engineering & computing
Jan 2, 2020
Cardiologists can acquire important information related to patients' cardiac health using carotid artery stiffness, its lumen diameter (LD), and its carotid intima-media thickness (cIMT). The sonographers primarily concern about the location of the a...
Perioperative morbidity is a public health priority, and surgical volume is increasing rapidly. With advances in technology, there is an opportunity to research the utility of a telemedicine-based control center for anesthesia clinicians that assess...
Journal of chemical information and modeling
Nov 22, 2019
New computational approaches for virtual screening applications are constantly being developed. However, before a particular tool is used to search for new active compounds, its effectiveness in the type of task must be examined. In this study, we co...
Computer methods and programs in biomedicine
Nov 19, 2019
BACKGROUND AND OBJECTIVE: Surgical skill assessment aims to objectively evaluate and provide constructive feedback for trainee surgeons. Conventional methods require direct observation with assessment from surgical experts which are both unscalable a...
The usefulness of genomic prediction in crop and livestock breeding programs has prompted efforts to develop new and improved genomic prediction algorithms, such as artificial neural networks and gradient tree boosting. However, the performance of th...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Oct 11, 2019
In recent years, electromyography (EMG)-based practical myoelectric interfaces have been developed to improve the quality of daily life for people with physical disabilities. With these interfaces, it is very important to decode a user's movement int...
We present a novel algorithm for Fast Registration Of image Groups (FROG), applied to large 3D image groups. Our approach extracts 3D SURF keypoints from images, computes matched pairs of keypoints and registers the group by minimizing pair distances...
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