AIMC Topic: Bone Neoplasms

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Diagnostic accuracy of ChatGPT-4 in orthopedic oncology: a comparative study with residents.

The Knee
BACKGROUND: Artificial intelligence (AI) is increasingly being explored for its potential role in medical diagnostics. ChatGPT-4, a large language model (LLM) with image analysis capabilities, may assist in histopathological interpretation, but its a...

Comparison of CNNs and Transformer Models in Diagnosing Bone Metastases in Bone Scans Using Grad-CAM.

Clinical nuclear medicine
PURPOSE: Convolutional neural networks (CNNs) have been studied for detecting bone metastases on bone scans; however, the application of ConvNeXt and transformer models has not yet been explored. This study aims to evaluate the performance of various...

Identification and validation of HOXC6 as a diagnostic biomarker for Ewing sarcoma: insights from machine learning algorithms and experiments.

Frontiers in immunology
INTRODUCTION: Early diagnosis of Ewing sarcoma (ES) is critical for improving patient prognosis. However, the accurate diagnosis of ES remains challenging, underscoring the need for novel diagnostic biomarkers to enhance diagnostic precision and reli...

Improved gated recurrent unit-based osteosarcoma prediction on histology images: a meta-heuristic-oriented optimization concept.

Scientific reports
The major prevalent primary bone cancer is osteosarcoma. Preoperative chemotherapy is accompanied by resection as part of the normal course of treatment. The diagnosis and treatment of patients are based on the chemotherapy reaction. Contrarily, chem...

A deep learning model for classification of chondroid tumors on CT images.

BMC cancer
BACKGROUND: Differentiating chondroid tumors is crucial for proper patient management. This study aimed to develop a deep learning model (DLM) for classifying enchondromas, atypical cartilaginous tumors (ACT), and high-grade chondrosarcomas using CT ...

AI in radiological imaging of soft-tissue and bone tumours: a systematic review evaluating against CLAIM and FUTURE-AI guidelines.

EBioMedicine
BACKGROUND: Soft-tissue and bone tumours (STBT) are rare, diagnostically challenging lesions with variable clinical behaviours and treatment approaches. This systematic review aims to provide an overview of Artificial Intelligence (AI) methods using ...

Automatic detecting multiple bone metastases in breast cancer using deep learning based on low-resolution bone scan images.

Scientific reports
Whole-body bone scan (WBS) is usually used as the effective diagnostic method for early-stage and comprehensive bone metastases of breast cancer. WBS images with breast cancer bone metastasis have the characteristics of low resolution, small foregrou...

Accuracy of artificial intelligence in detecting tumor bone metastases: a systematic review and meta-analysis.

BMC cancer
BACKGROUND: Bone metastases (BM) represent a prevalent complication of tumors. Early and accurate diagnosis, however, is a significant hurdle for radiologists. Recently, artificial intelligence (AI) has emerged as a valuable tool to assist radiologis...

CT-Less Whole-Body Bone Segmentation of PET Images Using a Multimodal Deep Learning Network.

IEEE journal of biomedical and health informatics
In bone cancer imaging, positron emission tomography (PET) is ideal for the diagnosis and staging of bone cancers due to its high sensitivity to malignant tumors. The diagnosis of bone cancer requires tumor analysis and localization, where accurate a...

Identification of the shared gene signatures in retinoblastoma and osteosarcoma by machine learning.

Scientific reports
Osteosarcoma (OS) is the most prevalent secondary sarcoma associated with retinoblastoma (RB). However, the molecular mechanisms driving the interactions between these two diseases remain incompletely understood. This study aims to explore the transc...