AIMC Topic: Brain Neoplasms

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An intelligent brain tumor detection model using lightweight hybrid twin attentive pyramid convolutional network.

Scientific reports
Brain tumors (BTs) pose a serious threat to human health, and the optimized treatment and results depend on early and accurate detection. Although MRIs and other medical imaging technologies provide insightful information, it is still difficult to de...

Non-invasive identification of mesenchymal glioblastoma using quantitative radiomic features from advanced diffusion MRI: a preclinical-to-clinical transfer learning strategy.

European radiology experimental
BACKGROUND: Glioblastoma (GBM) is no longer regarded as a single disease, as distinct molecular subgroups exist, with the mesenchymal (MES) having the worst prognosis. As such, there is a critical need for noninvasive methods to determine GBM molecul...

Interpretable radiomics-based machine learning model for differentiating glioblastoma from primary central nervous system lymphoma using contrast-enhanced T1-weighted imaging.

Scientific reports
This study aimed to develop and validate an interpretable radiomics-based machine learning model using contrast-enhanced T1-weighted imaging (CE-T1WI) to differentiate glioblastoma (GB) from primary central nervous system lymphoma (PCNSL), while comp...

MRI-Based Quantification of Intratumoral Heterogeneity for Predicting Progression-Free Survival in Patients with Lung Cancer Brain Metastasis Receiving Radiotherapy.

AJNR. American journal of neuroradiology
BACKGROUND AND PURPOSE: Our aim was to investigate the potential of using MRI-based habitat features for predicting progression-free survival (PFS) in patients with lung cancer brain metastasis (LCBM) receiving radiotherapy.

Fuzzy guided ensemble inference system for brain tumor classification.

Brain research
The abnormal growth of cells inside or near the brain is called a brain tumor. Brain tumors can be benign (non-cancerous) or malignant (cancerous). Both these types can exert pressure on the surrounding brain tissue, increasing intracranial pressure....

Spatial-reprogramming derived GPNMB macrophages interact with COL6A3 fibroblasts to enhance vascular fibrosis in glioblastoma.

Genome medicine
BACKGROUND: Neoadjuvant therapy plays an important role in the treatment of glioblastoma (GBM), but a considerable proportion of patients remain unresponsive to the combination of immune checkpoint blockade (ICB) and antiangiogenic therapy. Understan...

Hierarchical multi-scale vision transformer model for accurate detection and classification of brain tumors in MRI-based medical imaging.

Scientific reports
Automated brain tumor detection represents a fundamental challenge in contemporary medical imaging, demanding both precision and computational feasibility for practical implementation. This research introduces a novel Vision Transformer (ViT) framewo...

Evaluation of (Z)-endoxifen as a potential therapy for glioblastoma multiforme through computational and experimental analyses.

Scientific reports
(Z)-endoxifen (endoxifen) is the active metabolite of tamoxifen. Endoxifen is a potent antiestrogen that binds and blocks estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ). Early-phase clinical trials have shown that endoxifen has promis...

Enhanced local feature extraction of lite network with scale-invariant CNN for precise segmentation of small brain tumors in MRI.

PloS one
Deep learning has emerged as the preeminent technique for semantic segmentation of brain MRI tumors. However, existing methods often rely on hierarchical downsampling to generate multi-scale feature maps, effectively capturing fine-grained global fea...

Enhanced brain tumor segmentation in medical imaging using multi-modal multi-scale contextual aggregation and attention fusion.

Scientific reports
Accurate segmentation of brain tumors from multi-modal MRI scans is critical for diagnosis, treatment planning, and disease monitoring. Tumor heterogeneity and inter-image variability across MRI sequences pose challenging problems to state-of-the-art...