AIMC Topic: Carcinoma, Renal Cell

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Multiomics in Renal Cell Carcinoma: Current Landscape and Future Directions for Precision Medicine.

Current urology reports
PURPOSE OF REVIEW: Renal cell carcinoma (RCC) is a prevalent and increasingly diagnosed malignancy associated with high mortality and recurrence rates. Traditional diagnostic and therapeutic approaches have limitations due to the disease's molecular ...

Tumor grade-titude: XGBoost radiomics paves the way for RCC classification.

European journal of radiology
This study aimed to develop and evaluate a non-invasive XGBoost-based machine learning model using radiomic features extracted from pre-treatment CT images to differentiate grade 4 renal cell carcinoma (RCC) from lower-grade tumours. A total of 102 R...

State of the art review of AI in renal imaging.

Abdominal radiology (New York)
Renal cell carcinoma (RCC) as a significant health concern, with incidence rates rising annually due to increased use of cross-sectional imaging, leading to a higher detection of incidental renal lesions. Differentiation between benign and malignant ...

Predicting Recurrence After Surgical Resection for High-Risk Localized Renal Cell Carcinoma: A Radiomics Clinical Integration Approach.

The Journal of urology
PURPOSE: Adjuvant immunotherapy for clear cell renal cell carcinoma (ccRCC) is controversial because of the absence of reliable biomarkers for identifying patients most likely to benefit. The aim of this study was to develop and validate a quantitati...

Predictive Model of Objective Response to Nivolumab Monotherapy for Advanced Renal Cell Carcinoma by Machine Learning Using Genetic and Clinical Data: The SNiP-RCC Study.

JCO clinical cancer informatics
PURPOSE: Anti-PD-1 antibodies are widely used for cancer treatment, including in advanced renal cell carcinoma (RCC). However, the therapeutic response varies among patients. This study aimed to predict tumor response to nivolumab anti-PD-1 antibody ...

Machine learning-based multiparametric CT radiomics for predicting microvascular invasion before nephrectomy in clear cell renal cell carcinoma.

Abdominal radiology (New York)
PURPOSE: This study aimed to investigate the value of integrating computed tomography (CT)-based tumor radiomics features with clinical parameters for preoperative prediction of microvascular invasion (MVI) in clear cell renal cell carcinoma (ccRCC).

Identifying potential risk genes for clear cell renal cell carcinoma with deep reinforcement learning.

Nature communications
Clear cell renal cell carcinoma (ccRCC) is the most prevalent type of renal cell carcinoma. However, our understanding of ccRCC risk genes remains limited. This gap in knowledge poses challenges to the effective diagnosis and treatment of ccRCC. To a...

Interpretable Machine Learning Radiomics Model Predicts 5-year Recurrence-Free Survival in Non-metastatic Clear Cell Renal Cell Carcinoma: A Multicenter and Retrospective Cohort Study.

Academic radiology
RATIONALE AND OBJECTIVES: To develop and validate a computed tomography (CT) radiomics-based interpretable machine learning (ML) model for predicting 5-year recurrence-free survival (RFS) in non-metastatic clear cell renal cell carcinoma (ccRCC).

Role of artificial intelligence in predicting the renal function after nephrectomy in renal cell carcinoma: a systematic review and meta-analysis.

International urology and nephrology
PURPOSE: To explore and assess the role of artificial intelligence (AI) in predicting the postoperative renal function in Renal Cell Carcinoma (RCC) patients undergoing nephrectomy.

Exploring the Incremental Value of Aorta Enhancement Normalization Method in Evaluating Renal Cell Carcinoma Histological Subtypes: A Multi-center Large Cohort Study.

Academic radiology
RATIONALE AND OBJECTIVES: The classification of renal cell carcinoma (RCC) histological subtypes plays a crucial role in clinical diagnosis. However, traditional image normalization methods often struggle with discrepancies arising from differences i...