International journal of biological sciences
38993563
Renal cell carcinoma (RCC) is frequently accompanied by tumor thrombus in the venous system with an extremely dismal prognosis. The current Tumor Node Metastasis (TNM) stage and Mayo clinical classification do not appropriately identify preference-s...
Journal of cellular and molecular medicine
39011666
Clear cell renal cell carcinoma (ccRCC), a prevalent kidney cancer form characterised by its invasiveness and heterogeneity, presents challenges in late-stage prognosis and treatment outcomes. Programmed cell death mechanisms, crucial in eliminating ...
Medical oncology (Northwood, London, England)
38981988
Renal cell carcinoma is a highly vascular tumor associated with vascular endothelial growth factor (VEGF) expression. The Vascular Endothelial Growth Factor -2 (VEGF-2) and its receptor was identified as a potential anti-cancer target, and it plays a...
There is an urgent clinical demand to explore novel diagnostic and prognostic biomarkers for renal cell carcinoma (RCC). We proposed deep learning-based artificial intelligence strategies. The study included 1752 whole slide images from multiple cent...
BACKGROUND: Tumor mutation burden (TMB) and VHL mutation play a crucial role in the management of patients with clear cell renal cell carcinoma (ccRCC), such as guiding adjuvant chemotherapy and improving clinical outcomes. However, the time-consumin...
OBJECTIVE: Accurate assessment of Fuhrman grade is crucial for optimal clinical management and personalized treatment strategies in patients with clear cell renal cell carcinoma (CCRCC). In this study, we developed a predictive model using ultrasound...
BACKGROUND: Some clinicopathological risk stratification systems (CRSSs) such as the leibovich score have been used to predict the postoperative prognosis of patients with clear cell renal cell carcinoma (ccRCC), but there are no reliable noninvasive...
BMC medical informatics and decision making
39285449
BACKGROUND: The population diagnosed with renal cell carcinoma, especially in Asia, represents 36.6% of global cases, with the incidence rate of renal cell carcinoma in Korea steadily increasing annually. However, treatment options for renal cell car...
International journal of surgery (London, England)
38896853
BACKGROUND: Current prognostic models have limited predictive abilities for the growing number of localized (stage I-III) ccRCCs. It is, therefore, crucial to explore novel preoperative recurrence prediction models to accurately stratify patients and...