AIMC Topic: Cell Survival
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Classification of particle trajectories in living cells: Machine learning versus statistical testing hypothesis for fractional anomalous diffusion.
Physical review. E
Sep 1, 2020
Single-particle tracking (SPT) has become a popular tool to study the intracellular transport of molecules in living cells. Inferring the character of their dynamics is important, because it determines the organization and functions of the cells. For...
In vitro monitoring of photoinduced necrosis in HeLa cells using digital holographic microscopy and machine learning.
Journal of the Optical Society of America. A, Optics, image science, and vision
Feb 1, 2020
Digital holographic microscopy supplemented with the developed cell segmentation and machine learning and classification algorithms is implemented for quantitative description of the dynamics of cellular necrosis induced by photodynamic treatment in ...
Practical and Safe Method of Long-Term Cryopreservation for Clinical Application of Human Adipose-Derived Mesenchymal Stem Cells Without a Programmable Freezer Or Serum.
Cryo letters
Jan 1, 2020
BACKGROUND: Adipose-derived mesenchymal stem cells (ADSCs) have emerged as a promising modality for cellular therapy. However, techniques of ADSC cryopreservation, which can facilitate their clinical application, haven't been established yet.
Neuroprotective effects of Suhexiang Wan on the in vitro and in vivo models of Parkinson's disease.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan
Dec 1, 2019
OBJECTIVE: To examine the role of KSOP1009 (a modified formulation of Suhexiang Wan essential oil) in an animal model of Parkinson's disease (PD) induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) injection.
Lyapunov functional for virus infection model with diffusion and state-dependent delays.
Mathematical biosciences and engineering : MBE
Jan 29, 2019
In this paper, a virus dynamics model with diffusion, state-dependent delays and a general nonlinear functional response is investigated. At first, the dynamical system is constructed on a nonlinear metric space. Then the stability of the interior eq...
Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model.
Pharmaceutical biology
Dec 1, 2018
CONTEXT: Allium senescens Linn. (Liliaceae) (ASL) has been traditionally used in Korea and other Asian countries for improving digestive and liver functions.
Potential Anticancer Activity of the Parasol Mushroom, Macrolepiota procera (Agaricomycetes), against the A549 Human Lung Cancer Cell Line.
International journal of medicinal mushrooms
Jan 1, 2018
Mushrooms comprise an unlimited source of active compounds that have beneficial health effects without known negative side effects and can potentially be used as important therapeutic products against cancer, which is the leading cause of death world...
Overview of the Biological Activities of a Methanol Extract from Wild Red Belt Conk, Fomitopsis pinicola (Agaricomycetes), Fruiting Bodies from Central Italy.
International journal of medicinal mushrooms
Jan 1, 2018
Fomitopsis pinicola (Sw.) P. Karst. (Fomitopsidaceae) is a medicinal mushroom with a variety of healthy properties. In this study we tested the radical scavenging activity and antimicrobial and anticancer potential of methanol extracts of F. pinicola...
HT29 Cells
Flavonoids
Chemical Fractionation
Phenols
Free Radical Scavengers
Agaricales
Microbial Sensitivity Tests
Antifungal Agents
Fruiting Bodies, Fungal
Methanol
Humans
THP-1 Cells
Cell Proliferation
Coriolaceae
Antineoplastic Agents
Biphenyl Compounds
Apoptosis
Phylogeny
Picrates
Cell Survival
[Y-27632 protects H9c2 cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy pathway].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
Nov 1, 2017
Objective To investigate the protective effect of preconditioning with Rho-kinase inhibitor Y-27632 on H9c2 cardiomyocytes against hypoxia/reoxygenation (H/R) injury, and explore its underlying mechanism. Methods H9c2 cardiomyocytes were divided into...
Identification of human flap endonuclease 1 (FEN1) inhibitors using a machine learning based consensus virtual screening.
Molecular bioSystems
Jul 25, 2017
Human Flap endonuclease1 (FEN1) is an enzyme that is indispensable for DNA replication and repair processes and inhibition of its Flap cleavage activity results in increased cellular sensitivity to DNA damaging agents (cisplatin, temozolomide, MMS, e...
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