Advanced materials (Deerfield Beach, Fla.)
Nov 25, 2015
Superparamagnetic nanoparticles and a functional, degradable polymer matrix based on poly(ethylene glycol) are combined to enable fully degradable magnetic microdevices for minimally invasive biomedical applications. A bioinspired helical microrobot ...
Endogenous ribonucleotides and deoxyribonucleotides are essential metabolites that play important roles in a broad range of key cellular functions. Their intracellular levels could also reflect the action of nucleoside analogues. We investigated the ...
CONTEXT: Earthworms have been used as a traditional medicine in China from thousands of years. In recent years, research has demonstrated that earthworm extracts might promote wound healing; however, its mechanism is still unknown.
Nanomedicine : nanotechnology, biology, and medicine
Sep 25, 2015
Predicting the size and toxicity of chitosan/streptokinase nanoparticles at various values of processing parameters was the aim of this study. For the first time, a comprehensive model could be developed to determine the cytotoxicity of the nanoparti...
Understanding the processes of mitochondrial dynamics (fission, fusion, biogenesis, and mitophagy) has been hampered by the lack of automated, deterministic methods to measure mitochondrial morphology from microscopic images. A method to quantify mit...
Natural deep eutectic solvents (NaDESs) was efficient and green for componential extraction of traditional Chinese medicine compared to conventional organic solvents. In this study, a total of nine NaDESs were synthesized and screened, and Proline-Ur...
Ecotoxicology and environmental safety
Jul 1, 2025
This study presents a comprehensive machine learning-driven analysis to understand and predict the toxicity of nanoparticles (NPs), a crucial aspect in ensuring the safe application of nanotechnology in medicine, pharmaceuticals, biotechnology, and v...
Lipid nanoparticles (LNPs) are highly effective carriers for gene therapies, including mRNA and siRNA delivery, due to their ability to transport nucleic acids across biological membranes, low cytotoxicity, improved pharmacokinetics, and scalability....
MOTIVATION: Predicting drug response is critical for precision medicine. Diverse methods have predicted drug responsiveness, as measured by the half-maximal drug inhibitory concentration (IC50), in cultured cells. Although IC50s are continuous, tradi...
CONTEXT: Traditionally, Hook. f. (Asteraceae) has been reported to be effective in cancer treatment which motivated the authors to explore the plant for novel anticancer compounds.
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