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Cerebral Cortex

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Interpretable machine learning approach for neuron-centric analysis of human cortical cytoarchitecture.

Scientific reports
The complexity of the cerebral cortex underlies its function and distinguishes us as humans. Here, we present a principled veridical data science methodology for quantitative histology that shifts focus from image-level investigations towards neuron-...

Accessing the brain with soft deployable electrocorticography arrays.

Science robotics
Soft robotics facilitates the deployment of large radial electrode arrays on the brain cortex through small craniotomies.

High-resolution CMOS-based biosensor for assessing hippocampal circuit dynamics in experience-dependent plasticity.

Biosensors & bioelectronics
Experiential richness creates tissue-level changes and synaptic plasticity as patterns emerge from rhythmic spatiotemporal activity of large interconnected neuronal assemblies. Despite numerous experimental and computational approaches at different s...

Comparing the Graphical Features of Simple Artificial Neural Networks and Cortical Development.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Brain development is characterized by changes in connections and information processing complexity. These changes inspire the training process of artificial neural network (ANN), which requires adjusting the neuron weights and biases to enhance effic...

A state-of-the-art review on deep learning for estimating eloquent cortex from resting-state fMRI.

Neurosurgical review
Deep learning algorithms have greatly improved our ability to estimate eloquent cortex regions from resting-state brain scans for patients about to undergo neurosurgery. The use of deep learning has the potential to fully automate functional mapping ...

Facemap: a framework for modeling neural activity based on orofacial tracking.

Nature neuroscience
Recent studies in mice have shown that orofacial behaviors drive a large fraction of neural activity across the brain. To understand the nature and function of these signals, we need better computational models to characterize the behaviors and relat...

A thermodynamical model of non-deterministic computation in cortical neural networks.

Physical biology
Neuronal populations in the cerebral cortex engage in probabilistic coding, effectively encoding the state of the surrounding environment with high accuracy and extraordinary energy efficiency. A new approach models the inherently probabilistic natur...

Enhancing neural encoding models for naturalistic perception with a multi-level integration of deep neural networks and cortical networks.

Science bulletin
Cognitive neuroscience aims to develop computational models that can accurately predict and explain neural responses to sensory inputs in the cortex. Recent studies attempt to leverage the representation power of deep neural networks (DNNs) to predic...

End-to-end deep learning approach to mouse behavior classification from cortex-wide calcium imaging.

PLoS computational biology
Deep learning is a powerful tool for neural decoding, broadly applied to systems neuroscience and clinical studies. Interpretable and transparent models that can explain neural decoding for intended behaviors are crucial to identifying essential feat...

An Audio-Visual Speech Separation Model Inspired by Cortico-Thalamo-Cortical Circuits.

IEEE transactions on pattern analysis and machine intelligence
Audio-visual approaches involving visual inputs have laid the foundation for recent progress in speech separation. However, the optimization of the concurrent usage of auditory and visual inputs is still an active research area. Inspired by the corti...