AIMC Topic: Cholangiocarcinoma
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A histopathology-based artificial intelligence system assisting the screening of genetic alteration in intrahepatic cholangiocarcinoma.
British journal of cancer
Dec 2, 2024
BACKGROUND: Targeted therapy for intrahepatic cholangiocarcinoma (ICC) shows superior survival outcomes but patients with certain targetable alterations are no more than 20%. Genetic alteration screening for all ICC patients is of high cost and not r...
Upfront surgery for intrahepatic cholangiocarcinoma: Prediction of futility using artificial intelligence.
Surgery
Sep 24, 2024
OBJECTIVE: We sought to identify patients at risk of "futile" surgery for intrahepatic cholangiocarcinoma using an artificial intelligence (AI)-based model based on preoperative variables.
Multimodal convolutional neural network-based algorithm for real-time detection and differentiation of malignant and inflammatory biliary strictures in cholangioscopy: a proof-of-concept study (with video).
Gastrointestinal endoscopy
Sep 13, 2024
BACKGROUND AND AIMS: Deep learning algorithms gained attention for detection (computer-aided detection [CADe]) of biliary tract cancer in digital single-operator cholangioscopy (dSOC). We developed a multimodal convolutional neural network (CNN) for ...
Biliary Tract Neoplasms
Cholestasis
Cholangitis
Convolutional Neural Networks
ROC Curve
Sensitivity and Specificity
Diagnosis, Differential
Male
Constriction, Pathologic
Video Recording
Middle Aged
Neural Networks, Computer
Bile Duct Neoplasms
Diagnosis, Computer-Assisted
Algorithms
Proof of Concept Study
Deep Learning
Female
Cholangiocarcinoma
Humans
Aged
Endoscopy, Digestive System
Using machine learning methods to investigate the impact of age on the causes of death in patients with early intrahepatic cholangiocarcinoma who underwent surgery.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Sep 11, 2024
BACKGROUND: The impact of age on the causes of death (CODs) in patients with early-stage intrahepatic cholangiocarcinoma (ICC) who had undergone surgery was analyzed in this study.
Artificial intelligence for ultrasonographic detection and diagnosis of hepatocellular carcinoma and cholangiocarcinoma.
Scientific reports
Sep 4, 2024
The effectiveness of ultrasonography (USG) in liver cancer screening is partly constrained by the operator's expertise. We aimed to develop and evaluate an AI-assisted system for detecting and classifying focal liver lesions (FLLs) from USG images. T...
Serum targeted metabolomics uncovering specific amino acid signature for diagnosis of intrahepatic cholangiocarcinoma.
Journal of pharmaceutical and biomedical analysis
Sep 2, 2024
Intrahepatic cholangiocarcinoma (iCCA) is a hepatobiliary malignancy which accounts for approximately 5-10 % of primary liver cancers and has a high mortality rate. The diagnosis of iCCA remains significant challenges owing to the lack of specific an...
Focal liver lesion diagnosis with deep learning and multistage CT imaging.
Nature communications
Aug 15, 2024
Diagnosing liver lesions is crucial for treatment choices and patient outcomes. This study develops an automatic diagnosis system for liver lesions using multiphase enhanced computed tomography (CT). A total of 4039 patients from six data centers are...
Mining the interpretable prognostic features from pathological image of intrahepatic cholangiocarcinoma using multi-modal deep learning.
BMC medicine
Jul 8, 2024
BACKGROUND: The advances in deep learning-based pathological image analysis have invoked tremendous insights into cancer prognostication. Still, lack of interpretability remains a significant barrier to clinical application.
Development of machine learning models for patients in the high intrahepatic cholangiocarcinoma incidence age group.
BMC geriatrics
Jun 25, 2024
BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) has a poor prognosis and is understudied. Based on the clinical features of patients with ICC, we constructed machine learning models to understand their importance on survival and to accurately deter...
A machine learning predictive model for recurrence of resected distal cholangiocarcinoma: Development and validation of predictive model using artificial intelligence.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
May 9, 2024
INTRODUCTION: Distal Cholangiocarcinoma (dCCA) represents a challenge in hepatobiliary oncology, that requires nuanced post-resection prognostic modeling. Conventional staging criteria may oversimplify dCCA complexities, prompting the exploration of ...
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