A simple gradient high-performance liquid chromatography with diode array detection (HPLC-DAD) method was used to simultaneously to analyze characteristics of six indicator compounds in the traditional Chinese medicine (TCM) formulation Wen-Qing-Yin ...
OBJECTIVES: To develop a liquid chromatography-tandem mass spectrometry （LC-MS/MS） analytical method for the determination of oleandrin in blood and liver tissues, which could be applied to the cases of death caused by oleander poisoning.
Microcystins (MCs), which are produced by eruptive cyanobacteria, seriously threaten the health of humans for their poisonousness. Herein, a facile strategy was introduced to synthesize the magnetic γ-cyclodextrin polymer (FeO@PDA@γ-CDP) composite an...
Journal of pharmaceutical and biomedical analysis
Dec 21, 2018
A new, rapid, simple and specific method to determine 5-chloro 8-hydroxyquinoline (5-HQ) and 5,7-dichloro 8-hydroxyquinoline (5,7-HQ) stability in swine feed was optimized and validated. A system consisting of an ACQUITY UPLC BEH C column (1.7 μm, 2....
Journal of pharmaceutical and biomedical analysis
Dec 15, 2018
In vitro incubation of rat liver microsomes with 30 μL of 100 μmol·L dapoxetine and 30 μL of 10, 100, 250, 500, 1000, 2500, or 5000 μg·mL Wuziyanzong pill was performed at 37 °C for 60 min. Dapoxetine concentration was analyzed by high performance li...
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Dec 14, 2018
Carbamazepine (CBZ) was considered as the drug of choice in the treatment for various forms of epilepsy, yet the non-negligible adverse effects of CBZ suspend as the major concern for rational and efficient clinical medication. This study developed a...
European journal of hospital pharmacy : science and practice
Dec 1, 2018
BACKGROUND: A combination of methylprednisolone sodium succinate and tropisetron hydrochloride is commonly used to treat the nausea and vomiting associated with antineoplastic therapy. The objective of this study was to investigate the stability of t...
Neutrophil gelatinase associated lipocalin (NGAL) is a protein that was found to be overexpressed in acute kidney injury (AKI). The rise in NGAL concentration, both in urine or plasma, appears earlier than for other classical renal function markers s...
European journal of hospital pharmacy : science and practice
Oct 20, 2018
OBJECTIVES: Although levetiracetam presents an easy dosing and tolerability, therapeutic drug monitoring may be recommended in certain situations. Measurement of levetiracetam in serum plasma is commonly done by high performance liquid chromatography...
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