Computational and mathematical methods in medicine
Jun 11, 2019
Hepatitis B surface antigen (HBsAg) seroclearance during treatment is associated with a better prognosis among patients with chronic hepatitis B (CHB). Significant gaps remain in our understanding on how to predict HBsAg seroclearance accurately and ...
This paper proposes two spatio-temporal epidemic network models based on popularity and similarity optimization (PSO), called r-SI and r-SIS, respectively, in which new connections take both popularity and similarity into account. In the spatial dime...
Computer methods and programs in biomedicine
Jun 10, 2019
BACKGROUND AND OBJECTIVE: The recognition of many sleep related pathologies highly relies on an accurate classification of sleep stages. Clinically, sleep stages are usually labelled by sleep experts through visually inspecting the whole-night polyso...
Recently it has been proposed that information in working memory (WM) may not always be stored in persistent neuronal activity but can be maintained in 'activity-silent' hidden states, such as synaptic efficacies endowed with short-term synaptic plas...
Longitudinal imaging biomarkers are invaluable for understanding the course of neurodegeneration, promising the ability to track disease progression and to detect disease earlier than cross-sectional biomarkers. To properly realize their potential, b...
IMPORTANCE: Deep learning has the potential to augment clinician performance in medical imaging interpretation and reduce time to diagnosis through automated segmentation. Few studies to date have explored this topic.
Neural networks : the official journal of the International Neural Network Society
Jun 4, 2019
We seek to (i) characterize the learning architectures exploited in biological neural networks for training on very few samples, and (ii) port these algorithmic structures to a machine learning context. The moth olfactory network is among the simples...
Computer methods and programs in biomedicine
Jun 4, 2019
BACKGROUND AND OBJECTIVE: Risk prediction models aim at identifying people at higher risk of developing a target disease. Feature selection is particularly important to improve the prediction model performance avoiding overfitting and to identify the...
In this work, random forest (RF), support vector machine, k-nearest neighbor and C4.5 decision tree, were used to establish classification models for predicting whether an unknown molecule is an inhibitor of human topoisomerase I (Top1) protein. All ...
Computational intelligence and neuroscience
Jun 3, 2019
The ensemble pruning system is an effective machine learning framework that combines several learners as experts to classify a test set. Generally, ensemble pruning systems aim to define a region of competence based on the validation set to select th...
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