Multiple imputation (MI) models can be improved with auxiliary covariates (ACs), but their performance in high-dimensional data remains unclear. We aimed to develop and compare high-dimensional MI (HDMI) methods using structured and natural language ...
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Dec 25, 2025
For patients with MRI-negative drug-resistant epilepsy, noninvasive localization of targets for transcranial electrical stimulation (tES) remains a clinical challenge. This study proposes a novel target localization approach that integrates electroen...
This simulation study shows how a set of working memory tasks can be acquired simultaneously through interaction between a stacked recurrent neural network (RNN) and multiple working memories. In these tasks, temporal patterns are provided, followed ...
Mathematical and computational modeling enables in silico testing of hypotheses, experimental design, and interventional strategies. However, building, sharing, and applying complex models require technical skills and software development knowledge t...
Journal of magnetic resonance imaging : JMRI
Dec 1, 2025
Over the past decade, several studies have explored the potential of magnetic resonance fingerprinting (MRF) for the quantification of brain hemodynamics, oxygenation, and perfusion. Recent advances in simulation models and reconstruction frameworks ...
Throughout the lifecycle of biopharmaceutical development and manufacturing, monoclonal antibodies (mAbs) are subjected to diverse interfacial stresses and encounter various container surfaces. These interactions can cause the formation of subvisible...
Selection of lead therapeutic molecules is often driven predominantly by pharmacological efficacy and safety. Candidate developability, such as biophysical properties that affect the formulation of the molecule into a product, is usually evaluated on...
UNLABELLED: Bone metastasis (BM) is a leading cause of morbidity and mortality in patients with prostate and renal cancer. The complex and dynamic biological processes driving its progression present significant challenges for both understanding and ...
Advances in wearable technologies and health interventions delivered by smartphones have greatly increased the accessibility of mobile health (mHealth) interventions. Micro-randomized trials (MRTs) are designed to assess the effectiveness of the mHea...
Sunflower protein hydrolysate (SPH), with 95 % reduced phenolic content, was studied for its protective effects against oxidative stress in intestinal cells (Caco-2). Produced via alcalase hydrolysis, SPH's molecular weight, amino acid composition, a...
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