Mathematical biosciences and engineering : MBE
Aug 21, 2024
In this paper, our main objective was to investigate the central pattern generator (CPG) neural network model for quadruped gait with time delay. First, we computed the normal form of the model on the center manifold, the bifurcation direction, and s...
Chemical biology & drug design
Aug 1, 2024
The process of developing new drugs is widely acknowledged as being time-intensive and requiring substantial financial investment. Despite ongoing efforts to reduce time and expenses in drug development, ensuring medication safety remains an urgent p...
Briefings in bioinformatics
Jul 25, 2024
Therapeutic antibody design has garnered widespread attention, highlighting its interdisciplinary importance. Advancements in technology emphasize the critical role of designing nanobodies and humanized antibodies in antibody engineering. However, cu...
Briefings in bioinformatics
Jul 25, 2024
Predicting the strength of promoters and guiding their directed evolution is a crucial task in synthetic biology. This approach significantly reduces the experimental costs in conventional promoter engineering. Previous studies employing machine lear...
Briefings in bioinformatics
Jul 25, 2024
Metabolic processes can transform a drug into metabolites with different properties that may affect its efficacy and safety. Therefore, investigation of the metabolic fate of a drug candidate is of great significance for drug discovery. Computational...
Nucleic acids research
Jul 5, 2024
Interaction with chemicals, present in drugs, food, environments, and consumer goods, is an integral part of our everyday life. However, depending on the amount and duration, such interactions can also result in adverse effects. With the increase in ...
Genomics, proteomics & bioinformatics
Jul 3, 2024
Gene expression profiling of new or modified cell lines becomes routine today; however, obtaining comprehensive molecular characterization and cellular responses for a variety of cell lines, including those derived from underrepresented groups, is no...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Studying the soft robot-tissue mechanical interaction in muscle stimulation devices poses a significant challenge due to the complex behavior of the materials involved. To advance this field, this paper models computationally three types of soft elas...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
EEG source imaging is an indispensable tool for non-invasive study of brain function. Existing methods mainly directly deal with the EEG inverse problem by imposing prior constraints. However, different brain activation patterns may produce similar p...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2024
Artificial intelligence & Computer vision have the potential to improve surgical training, especially for minimally invasive surgery by analyzing intraoperative and simulation videos for training or performance improvement purposes. Among these, tech...