UK Biobank is a large-scale prospective epidemiological study with all data accessible to researchers worldwide. It is currently in the process of bringing back 100,000 of the original participants for brain, heart and body MRI, carotid ultrasound an...
Biochemical and biophysical research communications
Oct 7, 2017
Here we report the development of a machine-learning model to predict binding affinity based on the crystallographic structures of protein-ligand complexes. We used an ensemble of crystallographic structures (resolution better than 1.5 Å resolution) ...
Top-coal caving technology is a productive and efficient method in modern mechanized coal mining, the study of coal-rock recognition is key to realizing automation in comprehensive mechanized coal mining. In this paper we propose a new discriminant a...
Recently, there has been an upsurge of attention focused on bias and its impact on specialized artificial intelligence (AI) applications. Allegations of racism and sexism have permeated the conversation as stories surface about search engines deliver...
As a specific kind of non-Euclidean metric lies in projective space, Cayley-Klein metric has been recently introduced in metric learning to deal with the complex data distributions in computer vision tasks. In this paper, we extend the original Cayle...
Translating the vast data generated by genomic platforms into accurate predictions of clinical outcomes is a fundamental challenge in genomic medicine. Many prediction methods face limitations in learning from the high-dimensional profiles generated ...
The goal of the present study was to apply deep learning algorithms to identify autism spectrum disorder (ASD) patients from large brain imaging dataset, based solely on the patients brain activation patterns. We investigated ASD patients brain imagi...
Cancer classification based on molecular level is a relatively routine research procedure with advances in high-throughput molecular profiling techniques. However, the number of genes typically far exceeds the number of the sample size in gene expres...
BMC medical informatics and decision making
Aug 22, 2017
BACKGROUND: Identifying patients with certain clinical criteria based on manual chart review of doctors' notes is a daunting task given the massive amounts of text notes in the electronic health records (EHR). This task can be automated using text cl...
Journal of forensic and legal medicine
Aug 12, 2017
In less than a decade, big data in medicine has become quite a phenomenon and many biomedical disciplines got their own tribune on the topic. Perspectives and debates are flourishing while there is a lack for a consensual definition for big data. The...
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