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Deep Brain Stimulation

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Decoding of Human Movements Based on Deep Brain Local Field Potentials Using Ensemble Neural Networks.

Computational intelligence and neuroscience
Decoding neural activities related to voluntary and involuntary movements is fundamental to understanding human brain motor circuits and neuromotor disorders and can lead to the development of neuromotor prosthetic devices for neurorehabilitation. Th...

Automated assessment of symptom severity changes during deep brain stimulation (DBS) therapy for Parkinson's disease.

IEEE ... International Conference on Rehabilitation Robotics : [proceedings]
Deep brain stimulation (DBS) is currently being used as a treatment for symptoms of Parkinson's disease (PD). Tracking symptom severity progression and deciding the optimal stimulation parameters for people with PD is extremely difficult. This study ...

A hierarchical structure for human behavior classification using STN local field potentials.

Journal of neuroscience methods
BACKGROUND: Classification of human behavior from brain signals has potential application in developing closed-loop deep brain stimulation (DBS) systems. This paper presents a human behavior classification using local field potential (LFP) signals re...

Nonlinear predictive control for adaptive adjustments of deep brain stimulation parameters in basal ganglia-thalamic network.

Neural networks : the official journal of the International Neural Network Society
The efficacy of deep brain stimulation (DBS) for Parkinson's disease (PD) depends in part on the post-operative programming of stimulation parameters. Closed-loop stimulation is one method to realize the frequent adjustment of stimulation parameters....

Characterization of the stimulus waveforms generated by implantable pulse generators for deep brain stimulation.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: To determine the circuit elements required to theoretically describe the stimulus waveforms generated by an implantable pulse generator (IPG) during clinical deep brain stimulation (DBS).

A review on microelectrode recording selection of features for machine learning in deep brain stimulation surgery for Parkinson's disease.

Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
OBJECTIVE: This study seeks to systematically review the selection of features and algorithms for machine learning and automation in deep brain stimulation surgery (DBS) for Parkinson's disease. This will assist in consolidating current knowledge and...

Automatic localization of the subthalamic nucleus on patient-specific clinical MRI by incorporating 7 T MRI and machine learning: Application in deep brain stimulation.

Human brain mapping
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has shown clinical potential for relieving the motor symptoms of advanced Parkinson's disease. While accurate localization of the STN is critical for consistent across-patients effective D...

A machine-learning approach to volitional control of a closed-loop deep brain stimulation system.

Journal of neural engineering
OBJECTIVE: Deep brain stimulation (DBS) is a well-established treatment for essential tremor, but may not be an optimal therapy, as it is always on, regardless of symptoms. A closed-loop (CL) DBS, which uses a biosignal to determine when stimulation ...

Microelectrode Recordings Validate the Clinical Visualization of Subthalamic-Nucleus Based on 7T Magnetic Resonance Imaging and Machine Learning for Deep Brain Stimulation Surgery.

Neurosurgery
BACKGROUND: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a proven and effective therapy for the management of the motor symptoms of Parkinson's disease (PD). While accurate positioning of the stimulating electrode is critical for ...

Machine learning-aided personalized DTI tractographic planning for deep brain stimulation of the superolateral medial forebrain bundle using HAMLET.

Acta neurochirurgica
BACKGROUND: Growing interest exists for superolateral medial forebrain bundle (slMFB) deep brain stimulation (DBS) in psychiatric disorders. The surgical approach warrants tractographic rendition. Commercial stereotactic planning systems use determin...