Journal of chemical information and modeling
Jul 8, 2025
Peptide toxicity prediction is a critical task in biomedical research, influencing drug safety and therapeutic development. Traditional methods, relying on sequence similarity or handcrafted features, struggle to capture the complex relationship betw...
The frequent global outbreaks of viral infectious diseases have significantly heightened the urgent demand for molecular testing at home. However, the labor-intensive sample preparation and nucleic acid amplification steps, along with the complexity ...
Nonsmall cell lung cancer (NSCLC) remains a leading cause of cancer-related mortality, with liquid biopsy emerging as a promising tool for noninvasive diagnostics. Extracellular vesicles (EVs) serve as molecular messengers of the tumor microenvironme...
Proceedings of the National Academy of Sciences of the United States of America
Jul 8, 2025
Glioma is the most common primary malignant brain tumor and preoperative genetic profiling is essential for the management of glioma patients. Our study focused on tumor regions segmentation and predicting the World Health Organization (WHO) grade, i...
As one of the most common and abundant post-transcriptional modifications, N-methyladenosine (mA) has been extensively studied for its essential regulatory role in gene expression and cell functions. The location of mA RNA modification sites, however...
Detecting skin melanoma in the early stage using dermoscopic images presents a complex challenge due to the inherent variability in images. Utilizing dermatology datasets, the study aimed to develop Automated Diagnostic Systems for early skin cancer ...
The precise diagnosis of heart disease represents a significant obstacle within the medical field, demanding the implementation of advanced diagnostic instruments and methodologies. This article conducts an extensive examination of the efficacy of di...
Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide, emphasizing the need for accurate and early diagnosis. Electrocardiograms (ECG) provide a non-invasive means of diagnosing various cardiac conditions. However, traditional m...
The American Sign Language Recognition Dataset is a pivotal resource for research in visual-gestural languages for American Sign Language and Sign-Language MNIST Dataset. The dataset contains over 64,000 images meticulously labeled with the correspon...
The health monitoring of the subsea-immersed tunnels is essential for the early detection of anomalies and the assurance of their long-term operational safety. This research examines sensor data to evaluate variations in critical parameters and their...
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