AIMC Topic: Deep Learning

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Integrative strategies in drug discovery: Harnessing genomics, deep learning, and computer-aided drug design.

Computational biology and chemistry
The development of novel drugs increasingly relies on advanced omics technologies, including genomics, transcriptomics, proteomics, and metabolomics. These approaches provide insights into genetic mutations, biomarkers, and disease pathways. However,...

Beyond current boundaries: Integrating deep learning and AlphaFold for enhanced protein structure prediction from low-resolution cryo-EM maps.

Computational biology and chemistry
Constructing atomic models from cryo-electron microscopy (cryo-EM) maps is a crucial yet intricate task in structural biology. While advancements in deep learning, such as convolutional neural networks (CNNs) and graph neural networks (GNNs), have sp...

Artificial intelligence model for application in dental traumatology.

European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry
BACKGROUND: In recent years, healthcare systems have witnessed a tremendous advancement in diagnostic tools and technologies. The advent of artificial intelligence (AI) has enabled a paradigm shift in the practice of health sciences particularly in m...

Artificial intelligence-enhanced electrocardiogram diastolic function grade predicts post-septal myectomy mortality in hypertrophic cardiomyopathy.

The Journal of thoracic and cardiovascular surgery
BACKGROUNDS: Diastolic dysfunction is an important pathophysiologic feature of hypertrophic cardiomyopathy that is often challenging to determine noninvasively. This study investigated whether a novel artificial intelligence-enabled electrocardiograp...

Integrating Motor Unit Activity With Deep Learning for Real-Time, Simultaneous and Proportional Wrist Angle and Grasp Force Estimation.

IEEE transactions on bio-medical engineering
OBJECTIVE: Myoelectric prostheses offer great promise in enabling amputees to perform daily activities independently. However, existing neural interfaces generally cannot simultaneously and proportionally decode kinematics and kinetics in real time, ...

Phantom-Based Ultrasound-ECG Deep Learning Framework for Prospective Cardiac Computed Tomography.

IEEE transactions on bio-medical engineering
OBJECTIVE: We present the first multimodal deep learning framework combining ultrasound (US) and electrocardiography (ECG) data to predict cardiac quiescent periods (QPs) for optimized computed tomography angiography gating (CTA).

Reduction of photobleaching effects in photoacoustic imaging using noise agnostic, platform-flexible deep-learning methods.

Journal of biomedical optics
SIGNIFICANCE: Molecular photoacoustic (PA) imaging with exogenous dyes faces a significant challenge due to the photobleaching of the dye that can compromise tissue visualization, particularly in 3D imaging. Addressing this limitation can revolutioni...

Ultrasound image-based contrastive fusion non-invasive liver fibrosis staging algorithm.

Abdominal radiology (New York)
OBJECTIVE: The diagnosis of liver fibrosis is usually based on histopathological examination of liver puncture specimens. Although liver puncture is accurate, it has invasive risks and high economic costs, which are difficult for some patients to acc...

Deep Separable Spatiotemporal Learning for Fast Dynamic Cardiac MRI.

IEEE transactions on bio-medical engineering
OBJECTIVE: Dynamic magnetic resonance imaging (MRI) plays an indispensable role in cardiac diagnosis. To enable fast imaging, the k-space data can be undersampled but the image reconstruction poses a great challenge of high-dimensional processing. Th...

ECG-SMART-NET: A Deep Learning Architecture for Precise ECG Diagnosis of Occlusion Myocardial Infarction.

IEEE transactions on bio-medical engineering
OBJECTIVE: In this paper we develop and evaluate ECG-SMART-NET for occlusion myocardial infarction (OMI) identification. OMI is a severe form of heart attack characterized by complete blockage of one or more coronary arteries requiring immediate refe...