AIMC Topic: Deep Learning

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Improved Prediction of Ligand-Protein Binding Affinities by Meta-modeling.

Journal of chemical information and modeling
The accurate screening of candidate drug ligands against target proteins through computational approaches is of prime interest to drug development efforts. Such virtual screening depends in part on methods to predict the binding affinity between liga...

Visualizing Plant Disease Distribution and Evaluating Model Performance for Deep Learning Classification with YOLOv8.

Pathogens (Basel, Switzerland)
This paper presents a novel methodology for plant disease detection using YOLOv8 (You Only Look Once version 8), a state-of-the-art object detection model designed for real-time image classification and recognition tasks. The proposed approach involv...

Unsupervised Deep Learning for Synthetic CT Generation from CBCT Images for Proton and Carbon Ion Therapy for Paediatric Patients.

Sensors (Basel, Switzerland)
Image-guided treatment adaptation is a game changer in oncological particle therapy (PT), especially for younger patients. The purpose of this study is to present a cycle generative adversarial network (CycleGAN)-based method for synthetic computed t...

Screening for severe coronary stenosis in patients with apparently normal electrocardiograms based on deep learning.

BMC medical informatics and decision making
BACKGROUND: Patients with severe coronary arterystenosis may present with apparently normal electrocardiograms (ECGs), making it difficult to detect adverse health conditions during routine screenings or physical examinations. Consequently, these pat...

Heterogeneous virus classification using a functional deep learning model based on transmission electron microscopy images.

Scientific reports
Viruses are submicroscopic agents that can infect other lifeforms and use their hosts' cells to replicate themselves. Despite having simplistic genetic structures among all living beings, viruses are highly adaptable, resilient, and capable of causin...

Attention-based multi-residual network for lung segmentation in diseased lungs with custom data augmentation.

Scientific reports
Lung disease analysis in chest X-rays (CXR) using deep learning presents significant challenges due to the wide variation in lung appearance caused by disease progression and differing X-ray settings. While deep learning models have shown remarkable ...

The development of an attention mechanism enhanced deep learning model and its application for body composition assessment with L3 CT images.

Scientific reports
Body composition assessment is very useful for evaluating a patient's status in the clinic, but recognizing, labeling, and calculating the body compositions would be burdensome. This study aims to develop a web-based service that could automate calcu...

A novel deep learning approach to identify embryo morphokinetics in multiple time lapse systems.

Scientific reports
The use of time lapse systems (TLS) in In Vitro Fertilization (IVF) labs to record developing embryos has paved the way for deep-learning based computer vision algorithms to assist embryologists in their morphokinetic evaluation. Today, most of the l...

ClickGen: Directed exploration of synthesizable chemical space via modular reactions and reinforcement learning.

Nature communications
Despite the significant potential of generative models, low synthesizability of many generated molecules limits their real-world applications. In response to this issue, we develop ClickGen, a deep learning model that utilizes modular reactions like ...