Major depressive disorder (MDD) is highly heterogeneous, posing challenges for effective treatment due to complex interactions between clinical symptoms and neurobiological features. To address this, we apply contrastive principal-component analysis ...
BACKGROUND: Major Depressive Disorder (MDD) is a prevalent mental health condition with significant societal impact. Structural magnetic resonance imaging (sMRI) and machine learning have shown promise in psychiatry, offering insights into brain abno...
Journal of neuroengineering and rehabilitation
May 25, 2025
BACKGROUND: Major Depressive Disorder is a leading cause of disability worldwide. An accurate assessment of depression severity is critical for diagnosis, treatment planning, and monitoring, yet current clinical tools are largely subjective, relying ...
Post-COVID-19, depression rates have risen sharply, increasing the need for early diagnosis using electroencephalogram (EEG) and deep learning. To tackle this, we developed a cloud-based computer-aided depression diagnostic (CCADD) system that utiliz...
Type 2 diabetes mellitus (T2DM) and Major depressive disorder (MDD) act as risk factors for each other, and the comorbidity of both significantly increases the all-cause mortality rate. Therefore, studying the diagnosis and treatment of diabetes with...
Major depressive disorder (MDD) is a widespread mental disorder that affects health. Many methods combining electroencephalography (EEG) with machine learning or deep learning have been proposed to objectively distinguish between MDD and healthy indi...
BACKGROUND: Cortical morphological abnormalities in schizophrenia (SCZ), major depressive disorder (MDD), and bipolar disorder (BD) have been identified in past research. However, their potential as objective biomarkers to differentiate these disorde...
Major depressive disorder (MDD) is a prevalent and debilitating mental health condition characterized by persistent feelings of sadness and loss of interest. Despite its high prevalence, the underlying molecular mechanisms remain poorly understood. T...
Major depressive disorder (MDD) is a multifactorial disorder involving genetic and environmental factors, with unclear pathogenesis. This study aims to explore the pathogenic pathway of MDD and its relationship with immune responses and to discover i...
Journal of psychopathology and clinical science
Apr 10, 2025
Individuals with major depressive disorder (MDD) experience fewer positive and more negative emotions and use fewer positive words to describe themselves. Natural language processing techniques have been used to predict depression, with pronoun and e...
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