Advances in experimental medicine and biology
39261436
The chapter provides an in-depth analysis of digital therapeutics (DTx) as a revolutionary approach to managing major depressive disorder (MDD). It discusses the evolution and definition of DTx, their application across various medical fields, regula...
BACKGROUND: Major depressive disorder (MDD) is a widespread mental health issue, impacting spatial and temporal aspects of brain activity. The neural mechanisms behind MDD remain unclear. To address this gap, we introduce a novel measure, spatiotempo...
One of the most prevalent psychiatric disorders is major depressive disorder (MDD), which increases the probability of suicidal ideation or untimely demise. Abnormal frontal hemodynamic changes detected by functional near-infrared spectroscopy (fNIRS...
BACKGROUND AND PURPOSE: Diagnosis of depression is based on tests performed by psychiatrists and information provided by patients or their relatives. In the field of machine learning (ML), numerous models have been devised to detect depression automa...
Mood disorders, particularly bipolar disorder (BD) and major depressive disorder (MDD), manifest changes in brain structure that can be detected using structural magnetic resonance imaging (MRI). Although structural MRI is a promising diagnostic tool...
Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology
39332081
OBJECTIVE: Predicting an individual's response to antidepressant medication remains one of the most challenging tasks in the treatment of major depressive disorder (MDD). Our objective was to use the large EMBARC study database to develop an electroe...
Previous studies have found alterations in the local regional homogeneity of brain activity in individuals diagnosed with major depressive disorder. However, many studies have failed to consider that even during resting states, brain activity is dyna...
BACKGROUNDS: Major depressive disorder (MDD) is a pervasive mental and mood disorder with complicated and heterogeneous etiology. Mitophagy, a selective autophagy of cells, specifically eliminates dysfunctional mitochondria. The mitochondria dysfunct...
Psychiatric diseases are bringing heavy burdens for both individual health and social stability. The accurate and timely diagnosis of the diseases is essential for effective treatment and intervention. Thanks to the rapid development of brain imaging...
BACKGROUND: Electroencephalography (EEG) is a noninvasive, cost-effective, and robust tool, which directly measures in vivo neuronal mass activity with high temporal resolution. Combined with state-of-the-art machine learning (ML) techniques, EEG rec...