AIMC Topic: Disease Progression

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Estimating individual treatment effect on disability progression in multiple sclerosis using deep learning.

Nature communications
Disability progression in multiple sclerosis remains resistant to treatment. The absence of a suitable biomarker to allow for phase 2 clinical trials presents a high barrier for drug development. We propose to enable short proof-of-concept trials by ...

Dermoscopic image segmentation based on Pyramid Residual Attention Module.

PloS one
We propose a stacked convolutional neural network incorporating a novel and efficient pyramid residual attention (PRA) module for the task of automatic segmentation of dermoscopic images. Precise segmentation is a significant and challenging step for...

Improving the Efficiency of Multistep Short-Term Electricity Load Forecasting via R-CNN with ML-LSTM.

Sensors (Basel, Switzerland)
Multistep power consumption forecasting is smart grid electricity management's most decisive problem. Moreover, it is vital to develop operational strategies for electricity management systems in smart cities for commercial and residential users. How...

Evaluation of Disability Progression in Multiple Sclerosis via Magnetic-Resonance-Based Deep Learning Techniques.

International journal of molecular sciences
Short-term disability progression was predicted from a baseline evaluation in patients with multiple sclerosis (MS) using their three-dimensional T1-weighted (3DT1) magnetic resonance images (MRI). One-hundred-and-eighty-one subjects diagnosed with M...

Unsupervised machine learning identifies predictive progression markers of IPF.

European radiology
OBJECTIVES: To identify and evaluate predictive lung imaging markers and their pathways of change during progression of idiopathic pulmonary fibrosis (IPF) from sequential data of an IPF cohort. To test if these imaging markers predict outcome.

COVID-19 diagnosis via chest X-ray image classification based on multiscale class residual attention.

Computers in biology and medicine
Aiming at detecting COVID-19 effectively, a multiscale class residual attention (MCRA) network is proposed via chest X-ray (CXR) image classification. First, to overcome the data shortage and improve the robustness of our network, a pixel-level image...

Atrous residual convolutional neural network based on U-Net for retinal vessel segmentation.

PloS one
Extracting features of retinal vessels from fundus images plays an essential role in computer-aided diagnosis of diseases, such as diabetes, hypertension, and cerebrovascular diseases. Although a number of deep learning-based methods have been used i...

Deep Learning-Based Computed Tomography Features in Evaluating Early Screening and Risk Factors for Chronic Obstructive Pulmonary Disease.

Contrast media & molecular imaging
This research aimed to investigate the diagnostic effect of computed tomography (CT) images based on a deep learning double residual convolution neural network (DRCNN) model on chronic obstructive pulmonary disease (COPD) and the related risk factors...

Deep learning methods to predict amyotrophic lateral sclerosis disease progression.

Scientific reports
Amyotrophic lateral sclerosis (ALS) is a highly complex and heterogeneous neurodegenerative disease that affects motor neurons. Since life expectancy is relatively low, it is essential to promptly understand the course of the disease to better target...

Predicting Topographic Disease Progression and Treatment Response of Pegcetacoplan in Geographic Atrophy Quantified by Deep Learning.

Ophthalmology. Retina
PURPOSE: To identify disease activity and effects of intravitreal pegcetacoplan treatment on the topographic progression of geographic atrophy (GA) secondary to age-related macular degeneration quantified in spectral-domain OCT (SD-OCT) by automated ...