AIMC Topic: Drug Compounding

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Prediction of Dissolution Data Integrated in Tablet Database Using Four-Layered Artificial Neural Networks.

Chemical & pharmaceutical bulletin
A large number of dissolution data were measured and integrated into a previously constructed tablet database composed of 14 kinds of compounds as model active pharmaceutical ingredients (APIs) with contents ranging from 10 to 80%. The database has c...

Development of an ANN optimized mucoadhesive buccal tablet containing flurbiprofen and lidocaine for dental pain.

Acta pharmaceutica (Zagreb, Croatia)
A novel mucoadhesive buccal tablet containing flurbiprofen (FLB) and lidocaine HCl (LID) was prepared to relieve dental pain. Tablet formulations (F1-F9) were prepared using variable quantities of mucoadhesive agents, hydroxypropyl methyl cellulose (...

[Stability of high-dose etoposide dilutions for use in hematopoietic stem cell transplantation conditioning regimens].

Journal de pharmacie de Belgique
High-dose etoposide is used in conditioning regimens for allogeneic stem cell transplantation. The limited stability of the drug induces barriers for its use for pharmacists, nurses and patients. When using a concentration of 10 mg/mL etoposide in ph...

Validation of an UV spectrophotometric assay for the quantification of polymyxin B in solid lipid nanoparticles.

Die Pharmazie
Polymyxins are efficient antibiotic drugs used for the treatment of Gram-negative bacterial infections. These compounds are not absorbed in the gastrointestinal tract and are responsible for serious toxicological effects. In order to enhance their th...

A three-year study of a first-generation chemotherapy-compounding robot.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists
PURPOSE: Results of a performance evaluation of an automated system for compounding antineoplastic preparations are reported.