AIMC Topic: Drug Delivery Systems
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An Intelligent DNA Nanorobot with Enhanced Protein Lysosomal Degradation of HER2.
Nano letters
Jun 5, 2019
DNA nanorobots have emerged as new tools for nanomedicine with the potential to ameliorate the delivery and anticancer efficacy of various drugs. DNA nanostructures have been considered one of the most promising nanocarriers. In the present study, we...
THPep: A machine learning-based approach for predicting tumor homing peptides.
Computational biology and chemistry
May 24, 2019
In the present era, a major drawback of current anti-cancer drugs is the lack of satisfactory specificity towards tumor cells. Despite the presence of several therapies against cancer, tumor homing peptides are gaining importance as therapeutic agent...
Biocompatible propulsion for biomedical micro/nano robotics.
Biosensors & bioelectronics
May 17, 2019
Micro/Nano robots have shown enormous potential for diverse biomedical applications, such as targeted delivery, in vivo biosensing, minimally invasive surgery and cell manipulation through extending their area of operation to various previously inacc...
The significance of artificial intelligence in drug delivery system design.
Advanced drug delivery reviews
May 6, 2019
Over the last decade, increasing interest has been attracted towards the application of artificial intelligence (AI) technology for analyzing and interpreting the biological or genetic information, accelerated drug discovery, and identification of th...
Swarm-Fuzzy Rule-Based Targeted Nano Delivery Using Bioinspired Nanomachines.
IEEE transactions on nanobioscience
Mar 21, 2019
Cooperative navigation and swarm decision making take center stage in a broad range of distributed applications with high-environmental and measurement uncertainties. Here, we propose a fuzzy carotid body-inspired nanonetwork (FCBN) of autonomous nan...
Frontiers of Medical Robotics: From Concept to Systems to Clinical Translation.
Annual review of biomedical engineering
Mar 1, 2019
Medical robotics is poised to transform all aspects of medicine-from surgical intervention to targeted therapy, rehabilitation, and hospital automation. A key area is the development of robots for minimally invasive interventions. This review provide...
Biodegradable Thermomagnetically Responsive Soft Untethered Grippers.
ACS applied materials & interfaces
Dec 20, 2018
Soft-robotic devices such as polymeric microgrippers offer the possibility for pick and place of fragile biological cargo in hard-to-reach conduits with potential applications in drug delivery, minimally invasive surgery, and biomedical engineering. ...
Hypoxia-responsive micelles self-assembled from amphiphilic block copolymers for the controlled release of anticancer drugs.
Journal of materials chemistry. B
Dec 12, 2018
Amphiphilic block copolymers poly(ethylene glycol)-block-poly(methacrylic acid-co-2-nitroimidazole methacrylate) (PEG-b-P(MAA-co-NIMA)) were synthesized by the combination of atom transfer radical polymerization (ATRP), hydrolysis and EDC reactions. ...
Assessment of ovulation synchronization protocols in goats and use of pregnancy specific protein B (PSPB) enzyme linked immunsorbent assay (ELISA) to determine kid number at birth.
Domestic animal endocrinology
Nov 30, 2018
The efficacy of several protocols for ovulation synchronization and timed artificial insemination (TAI) in goats was examined. In addition, the relationship between levels of pregnancy specific protein B (PSPB) during gestation assessed with a commer...
Goats
Pregnancy-Specific beta 1-Glycoproteins
Animals
Gonadotropin-Releasing Hormone
Estrus Synchronization
Pregnancy
Progesterone
Insemination, Artificial
Litter Size
Gestational Age
Pregnancy Outcome
Female
Ovulation
Delayed-Action Preparations
Enzyme-Linked Immunosorbent Assay
Drug Delivery Systems
Dinoprost
Equipment Reuse
Investigation of magnetic silica with thermoresponsive chitosan coating for drug controlled release and magnetic hyperthermia application.
Materials science & engineering. C, Materials for biological applications
Nov 30, 2018
In this study, a drug delivery system for chemo-hyperthermia applications is proposed and fabricated. The delivery system consists of magnetic-silica (MagSi) particles being encapsulated within a pH/thermo-responsive chitosan‑g‑N‑isopropylacrylamide ...
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