International journal of pharmaceutics
Sep 26, 2025
The advancement of sustainable and biocompatible materials has opened new avenues in drug delivery systems, especially through the integration of plant-based nanofiber biocomposites. These materials, derived from renewable sources such as cellulose, ...
Ovarian cancer is a global silent killer in women and is the second most common cause of gynecologic cancer-related deaths. Despite significant research and advances in treatment, ovarian cancer treatment remains a challenge, as it is diagnosed in an...
Artificial intelligence (AI) has the potential to transform nanoparticle development for drug delivery; however, existing strategies typically optimize either material selection or component ratios in isolation. To enable simultaneous optimization of...
Journal of controlled release : official journal of the Controlled Release Society
Sep 10, 2025
As three-dimensional (3D), physiologically relevant models, organoids are rapidly becoming revolutionary platforms in biomedical research. With their ability to recapitulate tissue architecture, disease heterogeneity, and patient-specific therapeutic...
International journal of pharmaceutics
Aug 28, 2025
Label-free characterization of nanoscale drug delivery systems remains a critical challenge in pharmaceutical research. Traditional analytical methods, such as cryo-electron microscopy, are labor-intensive, low-throughput, and often require labeling,...
Journal of controlled release : official journal of the Controlled Release Society
Aug 25, 2025
The clinical translation of DDS is still one of the most challenging issues for the further development of therapeutic breakthroughs, especially for cancer and complex diseases. This review provides a critical overview of the factors that influence t...
Biosimilar artificial mucus models that mimic native mucus facilitate efficient, lab-based drug diffusion studies, addressing the costly and challenging preclinical phase of drug development, especially for nano- and micro-scale particle-based coloni...
International journal of pharmaceutics
Aug 20, 2025
Chronic wounds represent a significant healthcare challenge characterized by complex pathophysiology and poor clinical outcomes. The latest progress in smart bioelectronic systems which include biosensing capabilities alongside controlled drug delive...
International journal of pharmaceutics
Aug 19, 2025
Nanoparticles (NPs) represent critical roles both for drug delivery systems and diagnostics. Nevertheless, due to interaction in a biological medium and specific consequences-like formation of protein corona (PC), changes may happen that have influen...
Journal of controlled release : official journal of the Controlled Release Society
Aug 18, 2025
Nano-sized drug delivery systems have emerged as a more effective, versatile means for improving cancer treatment. However, the complexity of drug delivery to cancer involves intricate interactions between physiological and physicochemical processes ...
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