AIMC Topic: Electrophoresis, Capillary

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Thread based electrofluidic platform for direct metabolite analysis in complex samples.

Analytica chimica acta
The application of electrophoresis upon commercial threads is investigated for development of low-cost diagnostics assays, designed for the matrix separation and quantification of low abundance metabolites in complex samples - in this work riboflavin...

A validated capillary electrophoretic method for the determination of indacaterol and its application to a pharmaceutical preparation.

Journal of food and drug analysis
Indacaterol is a new inhaled ultra-long acting β-agonist. It has been recently approved in the European Union for the treatment of chronic obstructive pulmonary disease. This paper reports, for the first time, a method for the determination and valid...

Parts-per-trillion detection of harmala alkaloids in Undaria pinnatifida algae by on-line solid phase extraction capillary electrophoresis mass spectrometry.

Analytica chimica acta
β-carboline alkaloids of the harmala group (HAlks)-a family of compounds with pharmacologic effects-can be found at trace levels (<25 μg kg algae) in the edible invasive algae Undaria pinnatifida, known commonly as wakame. In this study, we present a...

Polydopamine-assisted partial hydrolyzed poly(2-methyl-2-oxazolinze) as coating for determination of melamine in milk by capillary electrophoresis.

Talanta
Nitrogen-rich melamine (66% by mass) had been found to be illegally adulterated to milk products and animal feed in order to increase the apparent protein content, and ingestion of melamine may lead to the formation of kidney stones. Hence, the devel...

Investigation of six bioactive anthraquinones in slimming tea by accelerated solvent extraction and high performance capillary electrophoresis with diode-array detection.

Food chemistry
A rapid and effective method for effective separation and rapid simultaneous determination of six bioactive anthraquinones by capillary zone electrophoresis was developed. An accelerated solvent extraction procedure was used for the extraction of ant...

Improved analytical workflow towards machine learning supported N-glycomics-based biomarker discovery.

Talanta
The composition and function of glycans are very complex thus manual data interpretation of their structural elucidation is difficult. Capillary electrophoresis is one of the liquid phase separation techniques, which is most frequently used to addres...

Real-Time Eco-AI, Electrophoresis-Correlative Data-Dependent Acquisition with AI-Based Data Processing Broadens Access to Single-Cell Mass Spectrometry Proteomics.

Angewandte Chemie (International ed. in English)
Single-cell mass spectrometry (MS) offers unprecedented sensitivity for profiling cellular proteomes, yet widespread adoption is hindered by the cost of advanced instrumentation. Here, we broaden access to single-cell proteomics by combining capillar...

Explainable artificial intelligence in forensic DNA analysis: Alleles identification in challenging electropherograms using supervised machine learning methods.

Forensic science international. Genetics
Challenging samples in capillary electrophoresis (CE)-based short tandem repeat (STR) analysis often produce artefactual signals that cannot be completely filtered out by expert electropherogram (EPG) reading systems, complicating allele interpretati...

Classifying Type 2 Diabetes Using N-Glycan Profiling and Machine Learning Algorithms.

Studies in health technology and informatics
BACKGROUND: Type 2 diabetes (T2D) continues to present a global public health challenge due to its increasing prevalence. Early diagnosis is critical for preventing complications, but current screening methods often fail to detect early diabetic cond...