AIMC Topic: Energy Metabolism

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Serum Peroxisome Proliferator-activated Receptor Gamma Coactivator-1α Related to Myocardial Energy Expenditure in Patients With Chronic Heart Failure.

The American journal of the medical sciences
BACKGROUND: Peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α) plays key roles in controlling cardiac metabolism and function. Myocardial energy expenditure (MEE) can reflect myocardial energy metabolism and cardiac function. Wh...

Calibration and validation of accelerometer-based activity monitors: A systematic review of machine-learning approaches.

Gait & posture
BACKGROUND: Objective measures using accelerometer-based activity monitors have been extensively used in physical activity (PA) and sedentary behavior (SB) research. To measure PA and SB precisely, the field is shifting towards machine learning-based...

Comparison of the human-exosuit interaction using ankle moment and ankle positive power inspired walking assistance.

Journal of biomechanics
Previous ankle exoskeleton assistance techniques that were able to demonstrate metabolic reductions can be categorized into those that delivered moment profiles similar to the biological ankle moment throughout the stance phase, and others that deliv...

A wearable hip-assist robot reduces the cardiopulmonary metabolic energy expenditure during stair ascent in elderly adults: a pilot cross-sectional study.

BMC geriatrics
BACKGROUND: Stair ascent is one of the most important and challenging activities of daily living to maintain mobility and independence in elderly adults. Recently, various types of wearable walking assist robots have been developed to improve gait fu...

Exoskeleton assistance symmetry matters: unilateral assistance reduces metabolic cost, but relatively less than bilateral assistance.

Journal of neuroengineering and rehabilitation
BACKGROUND: Many gait impairments are characterized by asymmetry and result in reduced mobility. Exoskeletons could be useful for restoring gait symmetry by assisting only one leg. However, we still have limited understanding of the effects of unilat...

Energy-Optimal Human Walking With Feedback-Controlled Robotic Prostheses: A Computational Study.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Lower-limb amputees typically experience reduced mobility and higher metabolic rates than non-amputees. It may be possible to improve their mobility and metabolic rate with an optimized robotic prosthesis. Here, we use large-scale trajectory optimiza...

Autonomous multi-joint soft exosuit with augmentation-power-based control parameter tuning reduces energy cost of loaded walking.

Journal of neuroengineering and rehabilitation
BACKGROUND: Soft exosuits are a recent approach for assisting human locomotion, which apply assistive torques to the wearer through functional apparel. Over the past few years, there has been growing recognition of the importance of control individua...

Spine morphology and energetics: how principles from nature apply to robotics.

Bioinspiration & biomimetics
Inspired by the locomotive advantages that an articulated spine enables in quadrupedal animals, we explore and quantify the energetic effect that an articulated spine has in legged robots. We compare two model instances of a conceptual planar quadrup...

Biomechanical mechanisms underlying exosuit-induced improvements in walking economy after stroke.

The Journal of experimental biology
Stroke-induced hemiparetic gait is characteristically asymmetric and metabolically expensive. Weakness and impaired control of the paretic ankle contribute to reduced forward propulsion and ground clearance - walking subtasks critical for safe and ef...

Quantitative approaches to energy and glucose homeostasis: machine learning and modelling for precision understanding and prediction.

Journal of the Royal Society, Interface
Obesity is a major global public health problem. Understanding how energy homeostasis is regulated, and can become dysregulated, is crucial for developing new treatments for obesity. Detailed recording of individual behaviour and new imaging modaliti...