The American journal of the medical sciences
Dec 7, 2018
BACKGROUND: Peroxisome proliferator-activated receptor gamma coactivator-1α (PGC-1α) plays key roles in controlling cardiac metabolism and function. Myocardial energy expenditure (MEE) can reflect myocardial energy metabolism and cardiac function. Wh...
BACKGROUND: Objective measures using accelerometer-based activity monitors have been extensively used in physical activity (PA) and sedentary behavior (SB) research. To measure PA and SB precisely, the field is shifting towards machine learning-based...
Previous ankle exoskeleton assistance techniques that were able to demonstrate metabolic reductions can be categorized into those that delivered moment profiles similar to the biological ankle moment throughout the stance phase, and others that deliv...
BACKGROUND: Stair ascent is one of the most important and challenging activities of daily living to maintain mobility and independence in elderly adults. Recently, various types of wearable walking assist robots have been developed to improve gait fu...
Journal of neuroengineering and rehabilitation
Aug 9, 2018
BACKGROUND: Many gait impairments are characterized by asymmetry and result in reduced mobility. Exoskeletons could be useful for restoring gait symmetry by assisting only one leg. However, we still have limited understanding of the effects of unilat...
IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Jul 20, 2018
Lower-limb amputees typically experience reduced mobility and higher metabolic rates than non-amputees. It may be possible to improve their mobility and metabolic rate with an optimized robotic prosthesis. Here, we use large-scale trajectory optimiza...
Journal of neuroengineering and rehabilitation
Jul 13, 2018
BACKGROUND: Soft exosuits are a recent approach for assisting human locomotion, which apply assistive torques to the wearer through functional apparel. Over the past few years, there has been growing recognition of the importance of control individua...
Inspired by the locomotive advantages that an articulated spine enables in quadrupedal animals, we explore and quantify the energetic effect that an articulated spine has in legged robots. We compare two model instances of a conceptual planar quadrup...
Stroke-induced hemiparetic gait is characteristically asymmetric and metabolically expensive. Weakness and impaired control of the paretic ankle contribute to reduced forward propulsion and ground clearance - walking subtasks critical for safe and ef...
Journal of the Royal Society, Interface
Jan 24, 2018
Obesity is a major global public health problem. Understanding how energy homeostasis is regulated, and can become dysregulated, is crucial for developing new treatments for obesity. Detailed recording of individual behaviour and new imaging modaliti...
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