AIMC Topic: Epilepsy, Temporal Lobe

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Machine learning detects EEG microstate alterations in patients living with temporal lobe epilepsy.

Seizure
PURPOSE: Quasi-stable electrical distribution in EEG called microstates could carry useful information on the dynamics of large scale brain networks. Using machine learning techniques we explored if abnormalities in microstates can identify patients ...

Quantitative surface analysis of combined MRI and PET enhances detection of focal cortical dysplasias.

NeuroImage
OBJECTIVE: Focal cortical dysplasias (FCDs) often cause pharmacoresistant epilepsy, and surgical resection can lead to seizure-freedom. Magnetic resonance imaging (MRI) and positron emission tomography (PET) play complementary roles in FCD identifica...

Automated diagnosis of temporal lobe epilepsy in the absence of interictal spikes.

NeuroImage. Clinical
OBJECTIVE: To diagnose and lateralise temporal lobe epilepsy (TLE) by building a classification system that uses directed functional connectivity patterns estimated during EEG periods without visible pathological activity.

Detection of Interictal Discharges With Convolutional Neural Networks Using Discrete Ordered Multichannel Intracranial EEG.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Detection algorithms for electroencephalography (EEG) data, especially in the field of interictal epileptiform discharge (IED) detection, have traditionally employed handcrafted features, which utilized specific characteristics of neural responses. A...

Relationship between neuronal network architecture and naming performance in temporal lobe epilepsy: A connectome based approach using machine learning.

Brain and language
Impaired confrontation naming is a common symptom of temporal lobe epilepsy (TLE). The neurobiological mechanisms underlying this impairment are poorly understood but may indicate a structural disorganization of broadly distributed neuronal networks ...

Machine learning classification of mesial temporal sclerosis in epilepsy patients.

Epilepsy research
BACKGROUND AND PURPOSE: Novel approaches applying machine-learning methods to neuroimaging data seek to develop individualized measures that will aid in the diagnosis and treatment of brain-based disorders such as temporal lobe epilepsy (TLE). Using ...

Machine Learning of DTI Structural Brain Connectomes for Lateralization of Temporal Lobe Epilepsy.

Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
BACKGROUND AND PURPOSE: We analyzed the ability of a machine learning approach that uses diffusion tensor imaging (DTI) structural connectomes to determine lateralization of epileptogenicity in temporal lobe epilepsy (TLE).

Multimodal data and machine learning for surgery outcome prediction in complicated cases of mesial temporal lobe epilepsy.

Computers in biology and medicine
BACKGROUND: This study sought to predict postsurgical seizure freedom from pre-operative diagnostic test results and clinical information using a rapid automated approach, based on supervised learning methods in patients with drug-resistant focal sei...

Evaluation of machine learning algorithms for treatment outcome prediction in patients with epilepsy based on structural connectome data.

NeuroImage
The objective of this study is to evaluate machine learning algorithms aimed at predicting surgical treatment outcomes in groups of patients with temporal lobe epilepsy (TLE) using only the structural brain connectome. Specifically, the brain connect...

Impaired dendritic inhibition leads to epileptic activity in a computer model of CA3.

Hippocampus
Temporal lobe epilepsy (TLE) is a common type of epilepsy with hippocampus as the usual site of origin. The CA3 subfield of hippocampus is reported to have a low epileptic threshold and hence initiates the disorder in patients with TLE. This study co...