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Epithelium

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Effect of Transtympanic Injection of Melatonin on Cisplatin-Induced Ototoxicity.

The journal of international advanced otology
OBJECTIVE: Cisplatin is a chemotherapeutic agent that is widely used in cancer treatment. Numerous side effects have been detected, one of which is ototoxicity. Melatonin, a product of the pineal gland, has a neuroendocrinoimmunological role in verte...

Epithelium-Stroma Classification via Convolutional Neural Networks and Unsupervised Domain Adaptation in Histopathological Images.

IEEE journal of biomedical and health informatics
Epithelium-stroma classification is a necessary preprocessing step in histopathological image analysis. Current deep learning based recognition methods for histology data require collection of large volumes of labeled data in order to train a new neu...

Automated detection of cancer cells in effusion specimens by DNA karyometry.

Cancer cytopathology
BACKGROUND: The average sensitivity of conventional cytology for the identification of cancer cells in effusion specimens is only approximately 58%. DNA image cytometry (DNA-ICM), which exploits the DNA content of morphologically suspicious nuclei me...

Levels and building blocks-toward a domain granularity framework for the life sciences.

Journal of biomedical semantics
BACKGROUND: With the emergence of high-throughput technologies, Big Data and eScience, the use of online data repositories and the establishment of new data standards that require data to be computer-parsable become increasingly important. As a conse...

A dense multi-path decoder for tissue segmentation in histopathology images.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Segmenting different tissue components in histopathological images is of great importance for analyzing tissues and tumor environments. In recent years, an encoder-decoder family of convolutional neural networks has increasi...

Epithelium segmentation and automated Gleason grading of prostate cancer via deep learning in label-free multiphoton microscopic images.

Journal of biophotonics
In the current clinical care practice, Gleason grading system is one of the most powerful prognostic predictors for prostate cancer (PCa). The grading system is based on the architectural pattern of cancerous epithelium in histological images. Howeve...