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Extinction, Psychological

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Expanding the role of striatal cholinergic interneurons and the midbrain dopamine system in appetitive instrumental conditioning.

Journal of neurophysiology
The basal ganglia are a collection of subcortical nuclei thought to underlie a wide variety of vertebrate behavior. Although a great deal is known about the functional and physiological properties of the basal ganglia, relatively few models have been...

Acquisition and extinction of operant pain-related avoidance behavior using a 3 degrees-of-freedom robotic arm.

Pain
Ample empirical evidence endorses the role of associative learning in pain-related fear acquisition. Nevertheless, research typically focused on self-reported and psychophysiological measures of fear. Avoidance, which is overt behavior preventing the...

Decision making under uncertainty in a spiking neural network model of the basal ganglia.

Journal of integrative neuroscience
The mechanisms of decision-making and action selection are generally thought to be under the control of parallel cortico-subcortical loops connecting back to distinct areas of cortex through the basal ganglia and processing motor, cognitive and limbi...

Distinct signals in medial and lateral VTA dopamine neurons modulate fear extinction at different times.

eLife
Dopamine (DA) neurons are to encode reward prediction error (RPE), in addition to other signals, such as salience. While RPE is known to support learning, the role of salience in learning remains less clear. To address this, we recorded and manipulat...