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Fatty Liver

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Accurate and generalizable quantitative scoring of liver steatosis from ultrasound images scalable deep learning.

World journal of gastroenterology
BACKGROUND: Hepatic steatosis is a major cause of chronic liver disease. Two-dimensional (2D) ultrasound is the most widely used non-invasive tool for screening and monitoring, but associated diagnoses are highly subjective.

Liver Attenuation Assessment in Reduced Radiation Chest Computed Tomography.

Journal of computer assisted tomography
OBJECTIVE: This study aimed to evaluate the reliability of liver and spleen Hounsfield units (HU) measurements in reduced radiation computed tomography (RRCT) of the chest within the sub-millisievert range.

Deep-learning-based hepatic fat assessment (DeHFt) on non-contrast chest CT and its association with disease severity in COVID-19 infections: A multi-site retrospective study.

EBioMedicine
BACKGROUND: Hepatic steatosis (HS) identified on CT may provide an integrated cardiometabolic and COVID-19 risk assessment. This study presents a deep-learning-based hepatic fat assessment (DeHFt) pipeline for (a) more standardised measurements and (...

The quest for the missing links in fatty liver genetics: Deep learning to the rescue!

Cell reports. Medicine
Park, MacLean, et al. conduct an exome-wide association study of liver fat content in the Penn Medicine BioBank. By leveraging machine learning-assisted analysis of clinical CT scans to quantify steatosis, they uncover previously undescribed liver fa...

Liver fat analysis using optimized support vector machine with support vector regression.

Technology and health care : official journal of the European Society for Engineering and Medicine
BACKGROUND: Fatty liver disease is a common condition caused by excess fat in the liver. It consists of two types: Alcoholic Fatty Liver Disease, also called alcoholic steatohepatitis, and Non-Alcoholic Fatty Liver Disease (NAFLD). As per epidemiolog...

Parallelized ultrasound homodyned-K imaging based on a generalized artificial neural network estimator.

Ultrasonics
The homodyned-K (HK) distribution model is a generalized backscatter envelope statistical model for ultrasound tissue characterization, whose parameters are of physical meaning. To estimate the HK parameters is an inverse problem, and is quite compli...

Performance of an automated deep learning algorithm to identify hepatic steatosis within noncontrast computed tomography scans among people with and without HIV.

Pharmacoepidemiology and drug safety
PURPOSE: Hepatic steatosis (fatty liver disease) affects 25% of the world's population, particularly people with HIV (PWH). Pharmacoepidemiologic studies to identify medications associated with steatosis have not been conducted because methods to eva...

Deep Learning-Based Survival Analysis for Receiving a Steatotic Donor Liver Versus Waiting for a Standard Liver.

Transplantation proceedings
BACKGROUND: An emerging strategy to expand the donor pool is the use of a steatotic donor liver (SDLs; ≥ 30% macrosteatosis on biopsy). With the obesity epidemic and prevalence of nonalcoholic fatty liver disease, SDLs have been reported in 59% of al...

Improved assessment of donor liver steatosis using Banff consensus recommendations and deep learning algorithms.

Journal of hepatology
BACKGROUND & AIMS: The Banff Liver Working Group recently published consensus recommendations for steatosis assessment in donor liver biopsy, but few studies reported their use and no automated deep-learning algorithms based on the proposed criteria ...