AIMC Topic: Fibroblast Growth Factor 7

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Construction of a deep learning model and identification of the pivotal characteristics of FGF7- and MGST1- positive fibroblasts in heart failure post-myocardial infarction.

International journal of biological macromolecules Apr 19, 2025
Dysregulation of fibroblast function is closely associated with the occurrence of heart failure after myocardial infarction (post-MI HF). Myocardial fibrosis is a detrimental consequence of aberrant fibroblast activation and extracellular matrix depo...
Humans Animals Male Deep Learning Mice Fibroblasts Myocardial Infarction Heart Failure Gene Expression Regulation Fibroblast Growth Factor 7
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Screening of CAD-related secretory genes associated with type II diabetes based on comprehensive bioinformatics analysis and machine learning.

BMC cardiovascular disorders Nov 5, 2024
BACKGROUND: Type II diabetes mellitus (T2DM) is strongly linked with a heightened risk of coronary artery disease (CAD). Exploring biological targets common to T2DM and CAD is essential for CAD intervention strategies.
Humans Machine Learning Female Aged Male Middle Aged Gene Expression Profiling Transcriptome Diabetes Mellitus, Type 2 Single-Cell Analysis Gene Regulatory Networks Genetic Predisposition to Disease Computational Biology Databases, Genetic Coronary Artery Disease Myocytes, Cardiac Myocytes, Smooth Muscle Fibroblast Growth Factor 7
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6-Gingerol inhibits hair cycle via induction of MMP2 and MMP9 expression.

Anais da Academia Brasileira de Ciencias Jan 1, 2017
6-Gingerol is the major active constituent of ginger. In the current study, we aimed to investigate the mechanisms underlying the effects of 6-Gingerol on hair growth. Mice were randomly divided into five groups; after hair depilation (day 0), mice w...
Female Animals Male Mice Insulin-Like Growth Factor I Plant Extracts Mice, Inbred C57BL Transforming Growth Factor beta Matrix Metalloproteinase 9 Matrix Metalloproteinase 2 Vascular Endothelial Growth Factor A Catechols Random Allocation Fatty Alcohols Enzyme Induction Fibroblast Growth Factor 7 Hair Follicle
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