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Genomics

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An investigation of machine learning methods applied to genomic prediction in yellow-feathered broilers.

Poultry science
Machine learning (ML) methods have rapidly developed in various theoretical and practical research areas, including predicting genomic breeding values for large livestock animals. However, few studies have investigated the application of ML in broile...

DeepDualEnhancer: A Dual-Feature Input DNABert Based Deep Learning Method for Enhancer Recognition.

International journal of molecular sciences
Enhancers are cis-regulatory DNA sequences that are widely distributed throughout the genome. They can precisely regulate the expression of target genes. Since the features of enhancer segments are difficult to detect, we propose DeepDualEnhancer, a ...

Machine learning algorithms translate big data into predictive breeding accuracy.

Trends in plant science
Statistical machine learning (ML) extracts patterns from extensive genomic, phenotypic, and environmental data. ML algorithms automatically identify relevant features and use cross-validation to ensure robust models and improve prediction reliability...

Artificial intelligence and omics in malignant gliomas.

Physiological genomics
Glioblastoma multiforme (GBM) is one of the most common and aggressive type of malignant glioma with an average survival time of 12-18 mo. Despite the utilization of extensive surgical resections using cutting-edge neuroimaging, and advanced chemothe...

Neonatal bioethics, AI, and genomics.

Early human development
Artificial intelligence (AI) and synthetic biology will transform civilization. The only question is how. In this paper, I explore some recent developments in medical AI, genomics, and synthetic biology. I speculate about the implications of these te...

CNVoyant a machine learning framework for accurate and explainable copy number variant classification.

Scientific reports
The precise classification of copy number variants (CNVs) presents a significant challenge in genomic medicine, primarily due to the complex nature of CNVs and their diverse impact on rare genetic diseases (RGDs). This complexity is compounded by the...

Machine Learning-Aided Ultra-Low-Density Single Nucleotide Polymorphism Panel Helps to Identify the Tharparkar Cattle Breed: Lessons for Digital Transformation in Livestock Genomics.

Omics : a journal of integrative biology
Cattle breed identification is crucial for livestock research and sustainable food systems, and advances in genomics and artificial intelligence present new opportunities to address these challenges. This study investigates the identification of the ...

Prediction of antimicrobial resistance of Klebsiella pneumoniae from genomic data through machine learning.

PloS one
Antimicrobials, such as antibiotics or antivirals are medications employed to prevent and treat infectious diseases in humans, animals, and plants. Antimicrobial Resistance occurs when bacteria, viruses, and parasites no longer respond to these medic...

Interpreting cis-regulatory interactions from large-scale deep neural networks.

Nature genetics
The rise of large-scale, sequence-based deep neural networks (DNNs) for predicting gene expression has introduced challenges in their evaluation and interpretation. Current evaluations align DNN predictions with orthogonal experimental data, providin...

A deep learning approach to prediction of blood group antigens from genomic data.

Transfusion
BACKGROUND: Deep learning methods are revolutionizing natural science. In this study, we aim to apply such techniques to develop blood type prediction models based on cheap to analyze and easily scalable screening array genotyping platforms.